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Last update 05 Sep 2025
Hydrochlorothiazide/Ramipril
Last update 05 Sep 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms Altace HCT, Ramipril/hydrochlorothiazide, Triatec HCT + [1] |
Target |
Action inhibitors |
Mechanism ACE inhibitors(Angiotensin-converting enzyme inhibitors), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Italy (09 Aug 1997), |
Regulation- |
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Structure/Sequence
Molecular FormulaC23H32N2O5 |
InChIKeyHDACQVRGBOVJII-JBDAPHQKSA-N |
CAS Registry87333-19-5 |
View All Structures (2)
Related
5
Clinical Trials associated with Hydrochlorothiazide/RamiprilNCT05685277
Open-label With Blinding Bioanalytical Stage Randomized Crossover Two Period Two Sequences Single Dose Bioequivalence Study of Two Formulations Ramipril/Hydrochlorothiazide Tablets 10 mg/25 mg (Manufacturer: Pharmtechnology LLC, Republic of Belarus) and Tritace® Plus Tablets 10 mg/25 mg (Manufacturer: Sanofi S.p.A., Italy; Holder of the Registration Certificate: Sanofi-Aventis Deutschland GmbH, Germany) in Healthy Volunteers Under Fasting Conditions
ISRCTN05051235
Open, prospective, parallel, multicentre, randomized trial to evaluate the efficacy and safety of two ramipril 5mg+ hydrochlorothiazide 25 mg formulations (Naprix D® versus Triatec D®) in the treatment of mild to moderate hypertension
NCT00574834
Mechanisms of Reduced Ramipril on the Onset of Type 2 Diabetes Mellitis
100 Clinical Results associated with Hydrochlorothiazide/Ramipril
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100 Translational Medicine associated with Hydrochlorothiazide/Ramipril
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100 Patents (Medical) associated with Hydrochlorothiazide/Ramipril
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100 Deals associated with Hydrochlorothiazide/Ramipril
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External Link
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| - | - | - |
R&D Status
10 top approved records. to view more data
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| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Hypertension | Italy | 09 Aug 1997 |
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Clinical Result
Clinical Result
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