The most frequently prescribed drug products were reviewed for insights into prescribing and dispensing patterns for ambulatory patients. The indications for eight of the "top" drug products were considered to be pharmacologically or therapeutically questionable. The drug products were: tetracycline, systemic; Dimetapp; Empirin Compound with Codeine; Actified; Darvon Compound 65; Darvocet-N; Donnatal; and Keflex. Drug prescribing review and prescriber education are crucially needed, as well as formulary controls when feasible.

01 Mar 1977·American Journal of Health-System Pharmacy

Stability of aspirin in propoxyphene compound dosage forms

Article

Author: Goldberg, Ronald ; Nightingale, Cliaries H.

The stability of aspirin in propoxyphene compound capsules made by three manufacturers, stored under a variety of temperature and humidity conditions, was compared. The cotton packing was removed from 100-capsule bottles, and the containers were stored (capped) under the following conditions: 25 c37 C and 50 C at both high (90%) and low (10%) humidity. No desiccant was removed from the bottles if originally present. The products tested were Darvon Compound-65 (two formulations) (Lilly), SK-65 Compound (Smith Kline & French) and Dolene Compound-65 (Lederle). Under all conditions, the stability of aspirin in the SK-65 Compound product was greater than that of Darvon Compound-65 which in turn was greater than Dolene Compound-65. Further, the rate of aspirin decomposition was greater in the latter product than in the others.

01 May 1975·Current therapeutic research, clinical and experimental

Acetaminophen extra strength capsules versus propoxphene compound-65 versus placebo: a double-blind study of effectiveness and safety.

Article

Author: Smith, M T ; Bare, W W ; Miller, J M ; Levin, H M ; Berry, F N

100 Deals associated with Aspirin/Caffeine/Propoxyphene Hydrochloride

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Aspirin/Caffeine/Propoxyphene Hydrochloride

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