Delving into the Latest Updates on Adenovirus-Thymidine Kinase Gene Preparation(Shenzhen Tiandakang Gene Engineering/Wuhan Tiandakang Biotechnology) with Synapse

Overview

Basic Info

Drug Type

Oncolytic virus

Synonyms

ADV-TK(Shenzhen Tiandakang Gene Engineering/Wuhan Tiandakang Biotechnology), Recombinant Adenovirus-Herpes Simplex Virus Thymidine Kinase(Shenzhen Tiandakang Gene Engineering/Wuhan Tiandakang Biotechnology)

Target

thymidine kinase

Action

modulators

Mechanism

thymidine kinase modulators(Thymidine kinase modulators)

Therapeutic Areas

NeoplasmsDigestive System Disorders

Active Indication

Hepatocellular Carcinoma

Inactive Indication-

Originator Organization

Wuhan Tiandakang Biotechnology Co., Ltd.

Shenzhen Tiandakang Gene Engineering Co., Ltd.

Active Organization

Shenzhen Tiandakang Gene Engineering Co., Ltd.

Inactive Organization-

Drug Highest PhasePhase 3

First Approval Date-

Regulation-

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Primary objective: To compare the clinical survival efficacy of liver transplantation combined with ADV-TK preparations and liver transplantation alone in patients with advanced primary hepatocellular carcinoma. Secondary objective: To observe the safety of liver transplantation combined with ADV-TK preparations in patients with advanced primary hepatocellular carcinoma.

Start Date11 Sep 2013

Sponsor / Collaborator

Wuhan Tiandakang Biotechnology Co., Ltd.

[+1]

ChiCTR-ONRC-11001232

/ CompletedPhase 2

Phase II study of Recombinant Adenovirus-Herpes Simplex Virus Thymidine Kinase (ADV-TK) combined with Ganciclovir in recurrent head and neck cancer of late-stage

Start Date21 Dec 2007

Sponsor / Collaborator

Shenzhen Tiandakang Gene Engineering Co., Ltd.

ChiCTR-ONRC-11001233

/ CompletedPhase 2

Phase II study of Recombinant Adenovirus-Herpes Simplex Virus Thymidine Kinase (ADV-TK) combined with Ganciclovir in primary hepatocellular carcinoma

Start Date29 Nov 2007

Sponsor / Collaborator

Shenzhen Tiandakang Gene Engineering Co., Ltd.

100 Clinical Results associated with Adenovirus-Thymidine Kinase Gene Preparation(Shenzhen Tiandakang Gene Engineering/Wuhan Tiandakang Biotechnology)

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100 Translational Medicine associated with Adenovirus-Thymidine Kinase Gene Preparation(Shenzhen Tiandakang Gene Engineering/Wuhan Tiandakang Biotechnology)

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100 Patents (Medical) associated with Adenovirus-Thymidine Kinase Gene Preparation(Shenzhen Tiandakang Gene Engineering/Wuhan Tiandakang Biotechnology)

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1

Literatures (Medical) associated with Adenovirus-Thymidine Kinase Gene Preparation(Shenzhen Tiandakang Gene Engineering/Wuhan Tiandakang Biotechnology)

01 Aug 2011·Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

[Study on the progression of recombinant adenovirus-herpes simplex virus thymidine kinase adjuvant for HCC therapy].

Article

Author: Li, Ning

100 Deals associated with Adenovirus-Thymidine Kinase Gene Preparation(Shenzhen Tiandakang Gene Engineering/Wuhan Tiandakang Biotechnology)

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