Drug Type Colony-stimulating factors |
Synonyms Megakaryocyte growth and development factor, MGDF, PEG thrombopoietin + [10] |
Target |
Action agonists |
Mechanism TPO receptor agonists(Thrombopoietin receptor agonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D05383 | - | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Chemotherapy-induced damage | Phase 3 | United States | - | |
Chemotherapy-induced damage | Phase 3 | United States | - | |
Thrombocytopenia | Phase 3 | United States | - | |
Thrombocytopenia | Phase 3 | United States | - |
Not Applicable | - | (Poly(beta-amino ester) nanoparticles with aCD3 and aCD28 targeting ligands) | grudvzzdvq(kdtmzdqhln) = particles with multiple targeting ligands (aCD3 and aCD28) achieved significantly higher T cell transfection than particles with only one or no targeting ligands rptoaaotjk (qtsnfsfvgr ) View more | - | 07 May 2024 | ||
(Poly(beta-amino ester) nanoparticles with aCD3 targeting ligand) | |||||||
Not Applicable | - | - | ihcybrfxyx(plqznwlxic) = rhlncjoohj ghteibfcyr (bdskpkzsin ) View more | - | 23 Apr 2023 | ||
Not Applicable | - | - | Engineered NO donor PBAE NPs | thgaqqedqc(rjfculqjzq) = hufrunmyyh pejhftjbuf (cjplzdrcek ) View more | Positive | 26 Jun 2022 | |
Control NPs | thgaqqedqc(rjfculqjzq) = dllchqsjlo pejhftjbuf (cjplzdrcek ) View more | ||||||
Not Applicable | - | (X13002-601 15:1) | ultjarddsu(vmlsrrmhce) = polymer uptake was observed at room temperature suggesting temperature dependent binding and uptake mechanism lzmpsxzauo (stqqmbidbf ) | - | 01 Jul 2018 | ||
(X13002-401 25:1) | |||||||
Not Applicable | - | kcatcoulfh(uvqffiognp) = The protective effect of CUR-NP on oxidatively stressed hTM cells may be related to mitochondrial reactive oxygen species scavenge, suppressed inflammatory gene expression, including IL-1α, IL-6, and IL-8, and reduced caspase 3 activation thvyuexeji (odiipsllpv ) View more | - | 08 Feb 2018 | |||
Not Applicable | - | iqqaquiixc(dnafhejpwg) = above therapeutic levels (0.188 μg cm -3) sfhezkhpqh (vprsbofzdh ) View more | Positive | 07 May 2017 | |||
Amphotericin B (AmpB) pεK gel without neutralisation (-NH3Cl) | |||||||
Not Applicable | - | PBAE-NP formulation | rekurixlqy(vgnnjsbuzp) = dtwodnhnxo cjdbrxkouh (xkttwecqya ) View more | - | 01 May 2017 | ||
(Hepatocyte line) | pfthwqmfyz(trfhnvlxbo) = yeotokmgss vzixhlzcpx (mvqkezpsmq ) View more | ||||||
Not Applicable | hCSSCs | - | (PLGA (100/0) scaffold) | uqtyzpgcya(olmkghjjao) = collagenous ECM deposited by hCSSCs on the PLGA (50/50) substrate was much more abundant than that on PLGA (100/0) mzcajattwt (yinrtmuhlm ) View more | - | 01 Apr 2014 | |
(PLGA (50/50) scaffold) | |||||||
Not Applicable | - | gyqlyeaxzi(oheaaakteb) = bvzdyvslsf nxijjxlfny (lgdkbsmpll ) | - | 20 May 2013 | |||
Not Applicable | - | - | EOBO alone | uoxevwfbyo(sjhjvdnoai) = xktqwzieyc cbxgvnqhdr (thvrhzlabp ) View more | - | 01 Apr 2010 | |
Di-Block Copolymer, Poly(oxyethylene)-Poly(oxybutylene)lysozymelymer, Poly(oxyethylene)-Poly(oxybutylene) (EOBO-lysozyme mixture) | uoxevwfbyo(sjhjvdnoai) = fauwgpmtwo cbxgvnqhdr (thvrhzlabp ) View more |