Last update 28 Jun 2025

JWK-002

Overview

Basic Info

Drug Type
AAV based gene therapy
Synonyms
Recombinant adeno-associated virus 8 (AAV8) expressing human retinoschisin (RS1) gene (Genevector), JWK 002, JWK002
Target
XLRS1
Action
stimulants
Mechanism
XLRS1 stimulants(Retinoschisin stimulants)
Therapeutic Areas
Congenital DisordersEye DiseasesOther Diseases
Active Indication
Retinoschisis
Inactive Indication-
Originator Organization
Chengdu Genevector Biotechnology Co. Ltd.Chengdu Genevector Biotechnology Co. Ltd.
Active Organization
Chengdu Genevector Biotechnology Co. Ltd.Chengdu Genevector Biotechnology Co. Ltd.
West China HospitalWest China Hospital
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
RegulationOrphan Drug (United States), Rare Pediatric Disease (United States)
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Related

3
Clinical Trials associated with JWK-002
NCT06345898
/ RecruitingEarly Phase 1IIT
Clinical Study on the Safety and Efficacy of JWK002 Injection Administered as a Single Subretinal Injection in Subjects With X-linked Retinoschisis
ChiCTR2300076682
/ RecruitingNot ApplicableIIT
Clinical study on the safety and efficacy of JWK002 injection administered as a single subretinal injection in subjects with X-linked retinoschisis
CTR20252527
/ Not yet recruitingPhase 1/2
一项在X连锁视网膜劈裂症（XLRS）患者中评价JWK002注射液的安全性、耐受性和初步有效性的I/II期临床研究
[Translation] A Phase I/II clinical study to evaluate the safety, tolerability and preliminary efficacy of JWK002 injection in patients with X-linked retinoschisis (XLRS)
100 Clinical Results associated with JWK-002
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100 Translational Medicine associated with JWK-002
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100 Patents (Medical) associated with JWK-002
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100 Deals associated with JWK-002
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
RetinoschisisPhase 2
China
Chengdu Genevector Biotechnology Co. Ltd.Chengdu Genevector Biotechnology Co. Ltd.
26 Jun 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Regulation

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