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Last update 22 Mar 2025
HR-004
Last update 22 Mar 2025
Overview
Basic Info
Drug Type Autologous CAR-T |
Synonyms Anti-CD19 anti-CD22 bispecific CAR-T cell therapy (Hrain Biotechnology), Anti-CD19 anti-CD22 bispecific chimeric antigen receptor T cell therapy(Hrain Biotechnology), Anti-human CD19-CD22 T cell therapy(Hrain Biotechnology Co. Ltd.) + [3] |
Target |
Action modulators |
Mechanism CD19 modulators(B-lymphocyte antigen CD19 modulators), CD22 modulators(CD22 modulators), Immunologic cytotoxicity |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
4
Clinical Trials associated with HR-004NCT05651178
A Early Phase 1 Clinical Trial to Evaluate the Safety and Efficacy of Human CD19-CD22 Targeted T Cells Injection for Subjects with Central Nervous System Involvement of Refractory/Relapsed B Cell Malignancies
NCT05223686
A Phase I Clinical Study To Evaluate the Safety and Tolerability of Human CD19-CD22 Targeted T Cells Injection for In Subjects With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia.
NCT04303520
A Phase I Clinical Trial of T-Cells Targeting CD19 and CD22 for Subjects With CD19-positive Acute Lymphoblastic Leukemia
100 Clinical Results associated with HR-004
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100 Translational Medicine associated with HR-004
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100 Patents (Medical) associated with HR-004
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100 Deals associated with HR-004
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Central nervous system leukaemia | Phase 1 | China | 12 Aug 2022 | |
| Primary Central Nervous System Lymphoma | Phase 1 | China | 12 Aug 2022 | |
| Pre B-cell acute lymphoblastic leukemia | Phase 1 | China | 10 Feb 2022 | |
| Recurrent B Acute Lymphoblastic Leukemia | Phase 1 | China | 21 Jan 2022 | |
| Refractory B Acute Lymphoblastic Leukemia | Phase 1 | China | 21 Jan 2022 | |
| CD19 positive Acute Lymphoblastic Leukemia | Phase 1 | China | 03 May 2018 |
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