Last update 24 May 2025

Trimegestone/Estratriol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Estriol/trimegestone, EVE 116, EVE-116
Target
ER x PR
Action
agonists
Mechanism
ERs agonists(Estrogen receptors agonists), PR agonists(Progesterone receptor agonists)
Therapeutic Areas
Other Diseases
Active Indication
Contraception
Inactive Indication
Pregnancy
Originator Organization
Evestra, Inc.Evestra, Inc.
Active Organization
Evestra, Inc.Evestra, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC22H30O3
InChIKeyJUNDJWOLDSCTFK-MTZCLOFQSA-N
CAS Registry74513-62-5
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Related

1
Clinical Trials associated with Trimegestone/Estratriol
NCT03343912
/ CompletedPhase 1IIT
Dose-response Study With Three Vaginal Rings With Different Doses of Estriol and Trimegestone: Effect on Progesterone and Estradiol Levels in Healthy Females With Childbearing Potential
100 Clinical Results associated with Trimegestone/Estratriol
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100 Translational Medicine associated with Trimegestone/Estratriol
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100 Patents (Medical) associated with Trimegestone/Estratriol
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100 Deals associated with Trimegestone/Estratriol
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PregnancyPhase 2
Germany
Evestra, Inc.Evestra, Inc.
28 May 2018
ContraceptionPhase 2-
Evestra, Inc.Evestra, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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