Last update 12 Sep 2024

AXT1003

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AXT 1003, AXT-1003
Target
EZH2
Mechanism
EZH2 inhibitors(Histone-lysine N-methyltransferase EZH2 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [3]
Active Indication
Advanced Malignant Solid NeoplasmAdvanced cancerNon-Hodgkin Lymphoma+ [5]
Inactive Indication
Peripheral T-Cell Lymphoma
Originator Organization
Novartis AGNovartis AG
Active Organization
Axter Therapeutics (Tianjin) Co., Ltd.Axter Therapeutics (Tianjin) Co., Ltd.Axter Therapeutics (Beijing) Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-

Related

3
Clinical Trials associated with AXT1003
NCT06484985 / Not yet recruitingPhase 1
An Open-label, Multicenter, Phase I Safety Study of AXT-1003 in Subjects With Advanced Malignant Tumors
NCT05965505 / TerminatedPhase 1
An Open-Label, Multicenter, Phase I Study of AXT-1003 as a Single Agent in Adult Subjects With Relapsed/Refractory Non-Hodgkin Lymphomas
CTR20242194 / Not yet recruitingPhase 1
一项AXT-1003治疗晚期恶性肿瘤患者的开放标签、多中心、I期安全性研究
[Translation] An open-label, multicenter, phase I safety study of AXT-1003 in patients with advanced malignancies
100 Clinical Results associated with AXT1003
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100 Translational Medicine associated with AXT1003
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100 Patents (Medical) associated with AXT1003
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100 Deals associated with AXT1003
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
CN
Axter Therapeutics (Beijing) Co., Ltd.
01 Jul 2024
Advanced cancerPhase 1
CN
Axter Therapeutics (Beijing) Co., Ltd.
27 Jun 2024
Non-Hodgkin LymphomaPhase 1
CN
Axter Therapeutics (Beijing) Co., Ltd.
11 Aug 2023
Peripheral T-Cell LymphomaPhase 1
CN
Axter Therapeutics (Beijing) Co., Ltd.
20 Jul 2023
Extranodal NK-T-Cell LymphomaPhase 1
CN
Axter Therapeutics (Beijing) Co., Ltd.
-
Prostatic CancerPreclinical
CN
Axter Therapeutics (Tianjin) Co., Ltd.Axter Therapeutics (Tianjin) Co., Ltd.
19 Jul 2022
SarcomaPreclinical
CN
Axter Therapeutics (Tianjin) Co., Ltd.Axter Therapeutics (Tianjin) Co., Ltd.
19 Jul 2022
Stomach CancerPreclinical
CN
Axter Therapeutics (Tianjin) Co., Ltd.Axter Therapeutics (Tianjin) Co., Ltd.
19 Jul 2022
Follicular LymphomaPreclinical
US
Axter Therapeutics (Beijing) Co., Ltd.
30 Jan 2022
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Clinical Result

Indication
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Approval

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Regulation

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