Last update 12 Jun 2025

HDM-2012

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
HDM 2012, HDM2012
Target
MUC17 x Top I
Action
inhibitors
Mechanism
MUC17 inhibitors(mucin 17, cell surface associated inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Colorectal CancerMuc17 positive Stomach Cancer
Inactive Indication-
Originator Organization
Huadong Medicine Co., Ltd.Huadong Medicine Co., Ltd.
Active Organization
Huadong Medicine Co., Ltd.Huadong Medicine Co., Ltd.Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd.Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseIND Application
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with HDM-2012
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100 Translational Medicine associated with HDM-2012
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100 Patents (Medical) associated with HDM-2012
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100 Deals associated with HDM-2012
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerPreclinical
China
Huadong Medicine Co., Ltd.Huadong Medicine Co., Ltd.
27 Apr 2025
Muc17 positive Stomach CancerPreclinical
China
Huadong Medicine Co., Ltd.Huadong Medicine Co., Ltd.
27 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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