[Translation] A multicenter, randomized, double-blind, placebo-controlled phase III clinical trial to evaluate the protective efficacy of attenuated live herpes zoster vaccine in people aged 40 years and above
主要目的:评价接种带状疱疹减毒活疫苗30天后预防带状疱疹的保护效力。次要目的:评价接种带状疱疹减毒活疫苗后预防带状疱疹的保护效力及30天后预防实验室诊断带状疱疹的保护效力和接种后的安全性、免疫原性和免疫持久性。探索性目的:探索接种带状疱疹减毒活疫苗30天后预防/减轻带状疱疹后遗神经痛(PHN)的保护效力。
[Translation] Primary objective: To evaluate the protective efficacy of attenuated live zoster vaccine against herpes zoster 30 days after vaccination. Secondary objective: To evaluate the protective efficacy of attenuated live zoster vaccine against herpes zoster and the protective efficacy against laboratory-diagnosed herpes zoster 30 days after vaccination, as well as the safety, immunogenicity and immune persistence after vaccination. Exploratory objective: To explore the protective efficacy of attenuated live zoster vaccine against postherpetic neuralgia (PHN) 30 days after vaccination.