Last update 08 May 2025

HY-0005

Overview

Basic Info

Drug Type
Trispecific T-cell engager (TriTE)
Synonyms
Target
CD3 x MSLN x PDL1
Action
stimulants, inhibitors
Mechanism
CD3 stimulants(T cell surface glycoprotein CD3 stimulants), MSLN inhibitors(Mesothelin inhibitors), PDL1 inhibitors(Programmed death-ligand 1 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Sichuan Huiyu Pharmaceutical Co., Ltd.Sichuan Huiyu Pharmaceutical Co., Ltd.
Active Organization
Sichuan Huiyu Seacross Pharma Technology Ltd.
Inactive Organization
Sichuan Huiyu Pharmaceutical Co., Ltd.Sichuan Huiyu Pharmaceutical Co., Ltd.
License Organization-
Drug Highest PhaseIND Application
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with HY-0005
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100 Translational Medicine associated with HY-0005
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100 Patents (Medical) associated with HY-0005
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100 Deals associated with HY-0005
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmIND Application
China
Sichuan Huiyu Seacross Pharma Technology Ltd.
17 Apr 2025
NeoplasmsDiscovery
China
Sichuan Huiyu Pharmaceutical Co., Ltd.Sichuan Huiyu Pharmaceutical Co., Ltd.
18 Oct 2021
Solid tumorDiscovery
European Union
Sichuan Huiyu Pharmaceutical Co., Ltd.Sichuan Huiyu Pharmaceutical Co., Ltd.
18 Oct 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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