Last update 01 Aug 2026

Keap1 ASOs(Biogen/Ionis)

Overview

Basic Info

Drug Type
ASO
Synonyms-
Target
KEAP1
Action
modulators
Mechanism
KEAP1 modulators(Kelch-like ECH-associated protein 1 modulators)
Therapeutic Areas
Nervous System DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication-
Inactive Indication
Amyotrophic Lateral SclerosisRetinal Degeneration
Originator Organization
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.Biogen, Inc.Biogen, Inc.
Active Organization-
Inactive Organization
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.Biogen, Inc.Biogen, Inc.
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with Keap1 ASOs(Biogen/Ionis)
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100 Translational Medicine associated with Keap1 ASOs(Biogen/Ionis)
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100 Patents (Medical) associated with Keap1 ASOs(Biogen/Ionis)
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100 Deals associated with Keap1 ASOs(Biogen/Ionis)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Amyotrophic Lateral SclerosisPreclinical
United States
Biogen, Inc.Biogen, Inc.
04 Nov 2018
Amyotrophic Lateral SclerosisPreclinical
United States
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
04 Nov 2018
Retinal DegenerationPreclinical
United States
Biogen, Inc.Biogen, Inc.
04 Nov 2018
Retinal DegenerationPreclinical
United States
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
04 Nov 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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