Last update 29 Mar 2025

[18F]P17-059

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
Deuterated [18F]hexadeuterofluoropropyl-(+)-dihydrotetrabenazine, FLUORINE-18 P17 059, [18F]D6-FP-DTBZ
+ [1]
Target
VMAT2
Action
inhibitors
Mechanism
VMAT2 inhibitors(Synaptic vesicular amine transporter inhibitors)
Therapeutic Areas
Nervous System DiseasesEndocrinology and Metabolic Disease
Active Indication-
Inactive Indication
Parkinson Disease
Originator Organization
Five Eleven Pharma, Inc.
Active Organization-
Inactive Organization
Five Eleven Pharma, Inc.
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with [18F]P17-059
NCT03903549
/ CompletedPhase 1
A Positron Emission Tomography (PET) Study to Investigate [18F]D6-FP-DTBZ ([18F]P17-059) for Potential Use as a Radioligand for Vesicular Monoamine Transporter (VMAT2)
100 Clinical Results associated with [18F]P17-059
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100 Translational Medicine associated with [18F]P17-059
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100 Patents (Medical) associated with [18F]P17-059
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100 Deals associated with [18F]P17-059
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Parkinson DiseasePhase 1
United States
Five Eleven Pharma, Inc.
15 Jul 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
SNMMI2024
Not Applicable
-
-
D6-[18F]FP-(+)-DTBZ
hmgbtorvhy(pqjpebqlua) = a substantial reduction in VMAT2 uptake in the putamen cpfiotwumk (rhpuaznjxk )
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-
09 Jun 2024
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Clinical Trial

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Approval

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Regulation

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