Last update 08 May 2025

Anti-CTLA4 antibody-SIRPα Fusion protein(The University of Texas Southwestern Medical Center)

Overview

Basic Info

Drug Type
Antibody
Synonyms-
Target
CD47 x CTLA4
Action
inhibitors
Mechanism
CD47 inhibitors(Cluster of differentiation 47 inhibitors), CTLA4 inhibitors(Cytotoxic T-Lymphocyte-Associated Antigen 4 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Solid tumor
Originator Organization
The University of Texas Southwestern Medical CenterThe University of Texas Southwestern Medical Center
Active Organization-
Inactive Organization
The University of Texas Southwestern Medical CenterThe University of Texas Southwestern Medical Center
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Anti-CTLA4 antibody-SIRPα Fusion protein(The University of Texas Southwestern Medical Center)
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100 Translational Medicine associated with Anti-CTLA4 antibody-SIRPα Fusion protein(The University of Texas Southwestern Medical Center)
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100 Patents (Medical) associated with Anti-CTLA4 antibody-SIRPα Fusion protein(The University of Texas Southwestern Medical Center)
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1
Literatures (Medical) associated with Anti-CTLA4 antibody-SIRPα Fusion protein(The University of Texas Southwestern Medical Center)
04 Aug 2021Science Translational MedicineQ1 · MEDICINE
Dual targeting of CTLA-4 and CD47 on T reg cells promotes immunity against solid tumors
Q1 · MEDICINE
100 Deals associated with Anti-CTLA4 antibody-SIRPα Fusion protein(The University of Texas Southwestern Medical Center)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPreclinical
United States
The University of Texas Southwestern Medical CenterThe University of Texas Southwestern Medical Center
03 Aug 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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