Last update 26 Feb 2025

CPO-102

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
CPO 102, CPO-102
Target
CLDN18.2 x Tubulin
Mechanism
CLDN18.2 inhibitors(Claudin 18.2 inhibitors), Tubulin inhibitors
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Pancreatic CancerStomach Cancer
Inactive Indication
Advanced Gastric Adenocarcinoma
Originator Organization
Conjupro Biotherapeutics, Inc.Conjupro Biotherapeutics, Inc.
Active Organization
Conjupro Biotherapeutics, Inc.Conjupro Biotherapeutics, Inc.
Inactive Organization
CSPC Megalith Biopharmaceutial Co., Ltd.
Drug Highest PhasePreclinical
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC39H67N5O7
InChIKeyDASWEROEPLKSEI-UIJRFTGLSA-N
CAS Registry474645-27-7

Related

1
Clinical Trials associated with CPO-102
NCT05043987
/ WithdrawnPhase 1
A Phase 1, Multicenter, Dose Escalation and Dose Expansion Study to Evaluate Safety of CPO102, an Anti-claudin 18.2 Antibody-MMAE Drug Conjugate Administered Intravenously in Patients With Advanced Pancreatic and Gastric Cancers
100 Clinical Results associated with CPO-102
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100 Translational Medicine associated with CPO-102
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100 Patents (Medical) associated with CPO-102
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100 Deals associated with CPO-102
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Gastric AdenocarcinomaPhase 1-
Conjupro Biotherapeutics, Inc.Conjupro Biotherapeutics, Inc.
16 Nov 2022
Advanced Gastric AdenocarcinomaPhase 1-
CSPC Megalith Biopharmaceutial Co., Ltd.
16 Nov 2022
Pancreatic CancerPhase 1-
CSPC Megalith Biopharmaceutial Co., Ltd.
16 Nov 2022
Pancreatic CancerPhase 1-
Conjupro Biotherapeutics, Inc.Conjupro Biotherapeutics, Inc.
16 Nov 2022
Stomach CancerPreclinical
US
Conjupro Biotherapeutics, Inc.Conjupro Biotherapeutics, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Clinical Trial

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Approval

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Regulation

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