Delving into the Latest Updates on Potassium Permanganate with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

Potassium permanganate (JP17/USP)

Target-

Action-

Mechanism-

Therapeutic Areas

Other DiseasesImmune System DiseasesCongenital Disorders+ [1]

Active Indication

DisinfectantsDermatitis, Atopic

Inactive Indication-

Originator Organization-

Active Organization

Nikko Pharmaceutical Co., Ltd.University of Lund

Inactive Organization-

Drug Highest PhaseApproved

First Approval Date

Japan (01 Apr 1998),

Disinfectants

Regulation-

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Structure/Sequence

Molecular FormulaHKMnO4

InChIKeyIRMGUHBBVMQJKT-UHFFFAOYSA-M

CAS Registry7722-64-7

Periodontal Disease is a ubiquitous in nature affecting about 80% population of India. The Periodontal Disease is a multifactorial but the dental plaque is considered as main etiological agent.The dental plaque, a adhesive bacterial coating accumulate around and in between teeth, if not removed by effective daily brushing and flossing, plaque can cause Gum infection and tooth loss. Though, many scientific periodontal procedures are available to get the treatment but because of lack of man power and poor socioeconomic condition it is not possible for every group of population in our India.

Start Date01 Jun 2015

Sponsor / Collaborator-

100 Clinical Results associated with Potassium Permanganate

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100 Translational Medicine associated with Potassium Permanganate

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100 Patents (Medical) associated with Potassium Permanganate

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28,621

Literatures (Medical) associated with Potassium Permanganate

01 Jul 2025·Separation and Purification Technology

Efficient and stable removal of Pb (Ⅱ) by coal gasification fine slag oxidized with potassium permanganate

Author: Chu, Mo ; Liu, Yanyu ; Dong, Jianfei ; Shi, Xu ; Sun, Xingbo

After oxidation of coal gasification fine slag with potassium permanganate, a coal gasification fine slag-manganese oxide composite material,GFS-Mn, is obtained, which exhibits efficient and stable adsorption capabilities for heavy metal Pb (II).GFS-Mn was obtained by mixing and oscillating coal gasification fine slag with potassium permanganate solution for 8 h at 25^°C with GFS/KMnO_4(aq) ratio of 1:20.GFS-Mn showed the maximum adsorption capacity of 398.41 mg·g^-1 for Pb (II) due to the existence of the Mn-OH and -COOH groups on its surface.The adsorption for Pb (II) reached the equilibrium within 120 min and the GFS-Mn loaded with Pb (II) was eluted using pure water and acid solution (pH = 3 ∼ 6), indicating that the adsorption result is highly irreversible, and the adsorbed Pb (II) cannot be released into the environment.In order to further learn the adsorption mechanism of Pb (II) by GFS-Mn, the adsorbents were analyzed by Electron microscopy, Fourier-Transform IR Spectroscopy and X-ray photoelectron spectrometer.

01 Jul 2025·Separation and Purification Technology

Electrocatalysis degradation of tetracycline in a three-dimensional electrocatalysis reactor (3DER) with MnO2/Pd(OAC)2@CA particle electrodes: Influencing factors, degradation pathway and toxicity assessment

Author: Dong, Deming ; Wang, Zhuowen ; Liang, Dapeng ; Chen, Haijun ; Hua, Xiuyi ; Guo, Zhiyong ; Liu, Haiyang ; Zhao, Shiyi ; Qu, Jiao

The extensive use of antibiotics poses a significant risk to human health, and electrocatalysis has demonstrated effectiveness in treating antibiotic contamination.This study details the synthesis of MnO₂/Pd(OAC)₂@CA particle electrodes using a straightforward one-step sol-gel method and the development of a three-dimensional electrocatalytic reactor (3DER) to remove antibiotics from water.Under optimal conditions (1.5 g/L MnO₂/0.3%Pd(OAC)₂, pH 3 and 2.0 V), a degradation of 97.8% of tetracycline hydrochloride (TCH) at a concentration of 15 mg/L is achieved within 80 min.The rate constant in the 3DER (k = 0.0389) is 9.26 times greater than that in a two-dimensional electrocatalytic reactor (2DER) (k = 0.0043).After ten cycles of treatment, the degradation rate of TCH remains at 86.4%.Furthermore, under optimal conditions, the energy consumption of the 3DER is significantly lower than that reported in other studies, with an EEO value of only 0.033 kWh/m³.Radical scavenger experiments and ESR (EPR) studies identify the free radicals involved, including •OH, SO₄•^-, H*, and •O^-₂.Theor. calculations and toxicity assessment reveal a general reduction in the toxicity of the intermediate products formed during the electrocatalytic degradation of TCH.In summary, the MnO₂/Pd(OAC)₂@CA particle electrodes exhibit high electrocatalytic degradation efficiency, excellent recyclability and reusability.The 3DER constructed using particle electrodes demonstrates broad applicability and environmental friendliness, providing a novel solution for remediating antibiotic-contaminated water.

01 Jul 2025·Separation and Purification Technology

Scalable fabrication of graphene-basalt composite fabric via Layer-by-Layer deposition for efficient treatment of Cr(VI) − contaminated water

Author: Tong, Xin ; Zhou, Lingyun ; Zhang, Yujia ; Zeng, Zheng ; Dai, Yi ; Li, Shijiao ; Yang, Guangxu ; Xie, Yadian ; Tang, Xu ; Yu, Hanqing

The contamination of water with hexavalent chromium (Cr(VI)) poses a significant environmental and health threat.Basalt fiber (BF) is a high-strength, high-temperature-resistant, corrosion-resistant, and eco-friendly inorganic fiber material that shows promise for addressing such contamination.However, a key challenge lies in how to effectively modify its surface functionality and enhance the overall performance of fiber composites to improve adsorption efficiency, especially in large-scale applications.In this study, we present a scalable fabrication method for graphene-basal composite material using a layer-by-layer deposition technique.This process enables the mass production of highly efficient Cr(VI) adsorbents.It exhibited a Cr(VI) removal rate of up to 97.9 % within 2 h, making it a promising candidate for efficient Cr(VI) adsorption.The composite material, integrating the high surface area of graphene with the mech. strength and chem. stability of basalt, exhibits superior adsorption capacity and reusability in removing Cr(VI) from contaminated water.D. functional theory (DFT) calculations indicated that the synergistic interaction between GO and BF enhanced both the phys. and chem. adsorption of Cr(VI), facilitating its removal.Batch experiments demonstrate that the composite achieves rapid and efficient Cr(VI) removal across a wide range of pH levels and initial concentrationsThe simple and scalable fabrication process highlights the potential for practical applications in large-scale water treatment.Furthermore, this study provides insight into the mechanisms underlying the adsorption process, offering a sustainable, rapid, and cost-effective solution to heavy metal pollution in environmental water bodies.

100 Deals associated with Potassium Permanganate

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