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Last update 27 Feb 2026
SIM-0609
Last update 27 Feb 2026
Overview
Basic Info
Drug Type Antibody drug conjugate (ADC) |
Synonyms SCR A008, SCR-A008, SCRA008 + [2] |
Target |
Action antagonists, inhibitors |
Mechanism CDH17 antagonists(Cadherin-17 antagonists), TOP1 inhibitors(DNA topoisomerase I inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Structure/Sequence
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Related
1
Clinical Trials associated with SIM-0609NCT07265921
A Phase I First-in-Human, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0609 in Adult Participants With Locally Advanced/Metastatic Solid Tumors
100 Clinical Results associated with SIM-0609
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100 Translational Medicine associated with SIM-0609
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100 Patents (Medical) associated with SIM-0609
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100 Deals associated with SIM-0609
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Malignant Solid Neoplasm | Phase 1 | China | 07 Nov 2025 | |
| Solid tumor | Phase 1 | China | 31 Oct 2025 | |
| Locally Advanced Malignant Solid Neoplasm | IND Approval | China | 05 Sep 2025 | |
| Metastatic Solid Tumor | IND Approval | China | 05 Sep 2025 | |
| CDH17-positive Solid Tumor | Preclinical | China | 29 Apr 2025 | |
| Gastrointestinal Neoplasms | Preclinical | China | 29 Apr 2025 |
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Clinical Result
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Translational Medicine
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Deal
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Core Patent
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Clinical Trial
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Approval
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Biosimilar
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Regulation
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