Last update 24 May 2025

VTS-105

Overview

Basic Info

Drug Type
Trispecific T-cell engager (TriTE)
Synonyms
VTS105
Target
BCMA x CD3 x GPRC5D
Action
inhibitors, stimulants
Mechanism
BCMA inhibitors(B-cell maturation protein inhibitors), CD3 stimulants(T cell surface glycoprotein CD3 stimulants), GPRC5D inhibitors(G-protein coupled receptor family C group 5member D inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [1]
Active Indication
Systemic Lupus ErythematosusHematologic NeoplasmsMultiple Myeloma
Inactive Indication-
Originator Organization
Shanghai Chengfan Pharmaceutical Co. Ltd.Shanghai Chengfan Pharmaceutical Co. Ltd.
Active Organization
Shanghai Chengfan Pharmaceutical Co. Ltd.Shanghai Chengfan Pharmaceutical Co. Ltd.VelaVigo (Hong Kong) Limited
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with VTS-105
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100 Translational Medicine associated with VTS-105
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100 Patents (Medical) associated with VTS-105
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100 Deals associated with VTS-105
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Systemic Lupus ErythematosusPreclinical
China
VelaVigo (Hong Kong) Limited
28 Apr 2025
Systemic Lupus ErythematosusPreclinical
China
Shanghai Chengfan Pharmaceutical Co. Ltd.Shanghai Chengfan Pharmaceutical Co. Ltd.
28 Apr 2025
Hematologic NeoplasmsPreclinical
China
Shanghai Chengfan Pharmaceutical Co. Ltd.Shanghai Chengfan Pharmaceutical Co. Ltd.
25 Apr 2025
Multiple MyelomaPreclinical
China
Shanghai Chengfan Pharmaceutical Co. Ltd.Shanghai Chengfan Pharmaceutical Co. Ltd.
18 Apr 2025
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Clinical Result

Indication
Phase
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Clinical Trial

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Approval

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Biosimilar

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Regulation

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