Last update 22 Mar 2025

JCAR-018

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
Anti-CD22 chimeric antigen receptor T cell therapy ( National Cancer Institute/Opus Bio), Anti-CD22 human single chain variable fragment CAR T cell therapy ( National Cancer Institute/Opus Bio), Anti-CD22-human scFv CAR T cell therapy ( National Cancer Institute/Opus Bio)
+ [1]
Target
CD22
Action
inhibitors
Mechanism
CD22 inhibitors(CD22 inhibitors), Gene transference, T lymphocyte replacements
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
Acute Lymphoblastic LeukemiaNon-Hodgkin Lymphoma
Inactive Indication-
Originator Organization
National Cancer InstituteNational Cancer Institute
Active Organization
Juno Therapeutics, Inc.Juno Therapeutics, Inc.Opus Bio, Inc.
Inactive Organization
National Cancer InstituteNational Cancer Institute
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with JCAR-018
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100 Translational Medicine associated with JCAR-018
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100 Patents (Medical) associated with JCAR-018
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100 Deals associated with JCAR-018
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Lymphoblastic LeukemiaPhase 1
United States
National Cancer InstituteNational Cancer Institute
-
Acute Lymphoblastic LeukemiaPhase 1-
Opus Bio, Inc.
-
Acute Lymphoblastic LeukemiaPhase 1-
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
-
Non-Hodgkin LymphomaPhase 1
United States
National Cancer InstituteNational Cancer Institute
-
Non-Hodgkin LymphomaPhase 1-
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
-
Non-Hodgkin LymphomaPhase 1-
Opus Bio, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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