Last update 29 May 2025

NBL-020

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
NBL 020, NBL-020, NBL020
Target
TNFR2
Action
modulators
Mechanism
TNFR2 modulators(Tumor necrosis factor receptor superfamily member 1B modulators)
Therapeutic Areas
NeoplasmsHemic and Lymphatic DiseasesOther Diseases+ [6]
Active Indication
Cutaneous T-Cell LymphomaLiver metastasesAdvanced cancer+ [6]
Inactive Indication-
Originator Organization
Shanghai Xinshi Biomedical Co., Ltd.
Active Organization
Shanghai Xinshi Biomedical Co., Ltd.Novarock Biotherapeutics Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with NBL-020
NCT05877924
/ RecruitingPhase 1
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Anti-tumor Activity of NBL-020 Injection in Subjects With Advanced Malignant Tumors.
100 Clinical Results associated with NBL-020
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100 Translational Medicine associated with NBL-020
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100 Patents (Medical) associated with NBL-020
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100 Deals associated with NBL-020
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cutaneous T-Cell LymphomaPhase 1
China
Novarock Biotherapeutics Ltd.
15 Aug 2023
Liver metastasesPhase 1
China
Novarock Biotherapeutics Ltd.
15 Aug 2023
Advanced cancerPhase 1
China
Shanghai Xinshi Biomedical Co., Ltd.
14 Aug 2023
Solid tumorPhase 1
United States
Novarock Biotherapeutics Ltd.
23 Dec 2022
Hematologic NeoplasmsPhase 1
China
Novarock Biotherapeutics Ltd.
-
Breast CancerIND Approval
China
Shanghai Xinshi Biomedical Co., Ltd.
13 Feb 2023
Colonic CancerIND Approval
China
Shanghai Xinshi Biomedical Co., Ltd.
13 Feb 2023
Lung CancerIND Approval
China
Shanghai Xinshi Biomedical Co., Ltd.
13 Feb 2023
Ovarian CancerIND Approval
China
Shanghai Xinshi Biomedical Co., Ltd.
13 Feb 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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