Last update 19 Jan 2026

Dextromethorphan Hydrobromide/Guaifenesin/Naproxen Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
COX-1 x COX-2 x NMDA receptor x σ1 receptor
Action
inhibitors, antagonists, agonists
Mechanism
COX-1 inhibitors(Cyclooxygenase-1 inhibitors), COX-2 inhibitors(Cyclooxygenase-2 inhibitors), NMDA receptor antagonists(Glutamate [NMDA] receptor antagonists)
Therapeutic Areas
Nervous System DiseasesRespiratory DiseasesOther Diseases
Active Indication
CoughFeverPain+ [1]
Inactive Indication-
Originator Organization
RB Health (US) LLC
Active Organization
RB Health (US) LLC
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (22 Dec 2025),
CoughFeverPain+ [1]
Regulation-
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Structure/Sequence

Molecular FormulaC14H14NaO3
InChIKeyCNQOEXOJUIMDHW-FVGYRXGTSA-N
CAS Registry26159-34-2
View All Structures (3)

Related

100 Clinical Results associated with Dextromethorphan Hydrobromide/Guaifenesin/Naproxen Sodium
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100 Translational Medicine associated with Dextromethorphan Hydrobromide/Guaifenesin/Naproxen Sodium
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100 Patents (Medical) associated with Dextromethorphan Hydrobromide/Guaifenesin/Naproxen Sodium
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100 Deals associated with Dextromethorphan Hydrobromide/Guaifenesin/Naproxen Sodium
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cough
United States
RB Health (US) LLC
22 Dec 2025
Fever
United States
RB Health (US) LLC
22 Dec 2025
Pain
United States
RB Health (US) LLC
22 Dec 2025
Sputum excretion difficulty
United States
RB Health (US) LLC
22 Dec 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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