STSP-0902

This trial is a Phase I clinical study to evaluate the safety, tolerability, and pharmacokinetic (PK) characteristics of STSP-0902 ophthalmic solution in healthy subjects following single and multiple administrations. The study plans to enroll 80 healthy subjects and is divided into three stages: the single-dose study stage, the multiple-dose study stage, and the tear PK study stage. The single-dose and multiple-dose study stages are randomized, double-blind, placebo-controlled, dose-escalation designs, while the tear PK study stage is a single-dose, open-label design.

主要目的：评价STSP-0902滴眼液单次和多次给药在健康受试者中的全身和眼局部的安全性和耐受性。 次要目的： 1.评价STSP-0902滴眼液单次和多次给药在健康受试者中的系统药代动力学特征。 2.评价STSP-0902滴眼液单次给药在健康受试者中的眼局部药代动力学特征。 3.评价STSP-0902滴眼液单次和多次给药在健康受试者中的免疫原性。