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Last update 12 Nov 2025
Neoantigen specific TCR-T cell drug product(Alaunos Therapeutics, Inc.)
Last update 12 Nov 2025
Overview
Basic Info
Drug Type TCR-T Cell therapy |
Synonyms Neoantigen Targeted TCR-T |
Target |
Action inhibitors |
Mechanism Tumor-associated antigen inhibitors(Tumor-associated antigen inhibitors), Gene transference(Gene transference), T lymphocyte replacements |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 1/2 |
First Approval Date- |
Regulation- |
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Related
2
Clinical Trials associated with Neoantigen specific TCR-T cell drug product(Alaunos Therapeutics, Inc.)NCT05292859
Long-Term Follow-Up Study for Subjects Enrolled in the Phase I/II Study of Autologous T Cells Using the Sleeping Beauty System to Express T Cell Receptors (TCRs) Reactive Against Cancer-specific Mutations in Subjects With Solid Tumors
NCT05194735
Phase I/II Study of Autologous T Cells Engineered Using the Sleeping Beauty System to Express T-Cell Receptors (TCRs) Reactive Against Cancer-specific Mutations in Subjects With Solid Tumors
100 Clinical Results associated with Neoantigen specific TCR-T cell drug product(Alaunos Therapeutics, Inc.)
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100 Translational Medicine associated with Neoantigen specific TCR-T cell drug product(Alaunos Therapeutics, Inc.)
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100 Patents (Medical) associated with Neoantigen specific TCR-T cell drug product(Alaunos Therapeutics, Inc.)
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100 Deals associated with Neoantigen specific TCR-T cell drug product(Alaunos Therapeutics, Inc.)
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Adenocarcinoma of Lung | Phase 2 | United States | 04 Apr 2022 | |
| Bile Duct Neoplasms | Phase 2 | United States | 04 Apr 2022 | |
| Colorectal Cancer | Phase 2 | United States | 04 Apr 2022 | |
| Endometrial Carcinoma | Phase 2 | United States | 04 Apr 2022 | |
| Ovarian Cancer | Phase 2 | United States | 04 Apr 2022 | |
| Pancreatic Cancer | Phase 2 | United States | 04 Apr 2022 | |
| squamous cell lung carcinoma | Phase 2 | United States | 04 Apr 2022 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1/2 | 6 | TCR-T cell | xndlfjhtnb(kdclwufdfy) = luvmthtqgu ydztbwogsp (gazmtzmigq ) | Positive | 14 Aug 2023 | ||
Phase 1/2 | Neoplasms KRAS G12D Mutation | 1 | Cyclophosphamide+Fludarabine Phosphate+TCR-T | ijdmfotdtz(vvyomdxewo) = Grade 4 thrombocytopenia and grade 3 anemia occurred and were both attributed to the lymphodepletion regimen. zyivaweeve (jyssfnojiz ) View more | Positive | 21 Sep 2022 |
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