Last update 16 May 2025

Acetaminophen/Dextromethorphan/Hydrocodone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
HydrocoDex SR, Hydrocodone/paracetamol/dextromethorphan, EN-3232
+ [1]
Target
COXs x NMDA receptor x Opioid receptors
Action
inhibitors, antagonists, agonists
Mechanism
COX inhibitors(Cyclooxygenases inhibitors), NMDA receptor antagonists(Glutamate [NMDA] receptor antagonists), Opioid receptors agonists(Opioid receptors agonists)
Therapeutic Areas
Nervous System DiseasesSkin and Musculoskeletal DiseasesOther Diseases
Active Indication-
Inactive Indication
Musculoskeletal PainPainPain, Postoperative
Originator Organization
Endo International PlcEndo International Plc
Active Organization-
Inactive Organization
Endo Pharmaceuticals, Inc.Endo International PlcEndo International Plc
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC8H9NO2
InChIKeyRZVAJINKPMORJF-UHFFFAOYSA-N
CAS Registry103-90-2
View All Structures (3)

Related

100 Clinical Results associated with Acetaminophen/Dextromethorphan/Hydrocodone
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100 Translational Medicine associated with Acetaminophen/Dextromethorphan/Hydrocodone
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100 Patents (Medical) associated with Acetaminophen/Dextromethorphan/Hydrocodone
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100 Deals associated with Acetaminophen/Dextromethorphan/Hydrocodone
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Musculoskeletal PainPhase 2
United States
Endo Pharmaceuticals, Inc.
-
PainPhase 2-
Endo International PlcEndo International Plc
-
Pain, PostoperativePhase 2
United States
Endo Pharmaceuticals, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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