Last update 08 May 2025

PD-1 x TGFβR2 bispecific antibodies(Xencor)

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms-
Target
PD-1 x TGFBR2
Action
inhibitors
Mechanism
PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TGFBR2 inhibitors(Transforming growth factor beta receptor 2 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Solid tumor
Originator Organization
Xencor, Inc.Xencor, Inc.
Active Organization-
Inactive Organization
Xencor, Inc.Xencor, Inc.
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with PD-1 x TGFβR2 bispecific antibodies(Xencor)
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100 Translational Medicine associated with PD-1 x TGFβR2 bispecific antibodies(Xencor)
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100 Patents (Medical) associated with PD-1 x TGFβR2 bispecific antibodies(Xencor)
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100 Deals associated with PD-1 x TGFβR2 bispecific antibodies(Xencor)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPreclinical
United States
Xencor, Inc.Xencor, Inc.
12 Nov 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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