Goreisan, Goshuyuto, Tokishakuyakusan, and Keishibukuryogan are frequently used to treat migraines. Goreisan is also used to treat chronic subdural hematoma. Yokukansan and Keishikaryukotsuboreito are useful for alleviating the behavioral and psychological symptoms of dementia. Keishikajyutsubuto and Shinbuto are used to treat numbness and pain associated with peripheral neuropathy. Hangeshashinto has been successfully attempted to treat intractable hiccoughs. It is advisable to use an extract of stable quality in accordance with the rule of thumb described in the classics. However, awareness of side effects, such as pseudoaldosteronism caused by licorice, is important.

01 May 2022·Internal Medicine

Effective Treatment of Adult Parasomnias with Keishikaryukotsuboreito in Four Cases

Article

Author: Muramatsu, Shin-ichi ; Tamada, Mayumi ; Ueno, Shinji ; Watanabe, Kako

Parasomnias are undesirable behaviors or experiences during sleep that manifest clinically as abnormal behavior, emotions, and nightmares. We herein report four elderly parasomnia patients who were successfully treated for abnormal nocturnal behaviors, including rapid eye movement (REM) sleep behavior disorders, with Keishikaryukotsuboreito (KRB), a Japanese traditional herbal medicine. KRB resolved nocturnal violent behaviors and sleep walking without any adverse effects. In one patient, occipital dominant spike-wave complexes induced by 3-Hz photic stimulation were reduced after KRB treatment, suggesting that KRB has inhibitory effects on brain irritability. KRB may represent a safe therapeutic option for treating parasomnias in the elderly.

01 May 2017·Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Modern research and application of Longgu].

Review

Author: Hao, Xu-Liang ; Ji, Hai-Xia ; Xu, Wen-Wen ; Yang, Wei-Han ; Ni, Yan ; Du, Jia-Neng

Hops, the female inflorescences of the hop plant (Humulus lupulus), are widely used in the brewing industry to add bitterness and aroma to beer. Combining with the relevant literature, the chemical composition(resinae, volatile oil, polyphenol and polysaccharide) in hops and their pharmacological effects are reviewed in this paper so as to present some sights for further application research and development.

100 Deals associated with Guizhi Longgu Muli Decoction

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Indication	Country/Location	Organization	Date
Asthenopia	Japan	Ohsugi Pharmaceutical Co., Ltd.	22 Aug 1986
Enuresis	Japan	Ohsugi Pharmaceutical Co., Ltd.	22 Aug 1986
Sleep Initiation and Maintenance Disorders	Japan	Ohsugi Pharmaceutical Co., Ltd.	22 Aug 1986

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