Last update 02 May 2026

AHA-1031

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
AHA1031
Target
MICA x MICB
Action
inhibitors
Mechanism
MICA inhibitors(MHC class I polypeptide-related sequence A inhibitors), MICB inhibitors(MHC class I polypeptide-related sequence B inhibitors)
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication
STK11 Mutation Non-Small Cell Lung Cancer
Inactive Indication-
Originator Organization
The University of Texas Southwestern Medical CenterThe University of Texas Southwestern Medical CenterAakha BiologicsAakha BiologicsAlloy Therapeutics, Inc.
Active Organization
The University of Texas Southwestern Medical CenterThe University of Texas Southwestern Medical CenterAakha BiologicsAakha BiologicsAlloy Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with AHA-1031
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100 Translational Medicine associated with AHA-1031
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100 Patents (Medical) associated with AHA-1031
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100 Deals associated with AHA-1031
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
STK11 Mutation Non-Small Cell Lung CancerPreclinical
United States
The University of Texas Southwestern Medical CenterThe University of Texas Southwestern Medical Center
06 Jan 2025
STK11 Mutation Non-Small Cell Lung CancerPreclinical
United States
Aakha BiologicsAakha Biologics
06 Jan 2025
STK11 Mutation Non-Small Cell Lung CancerPreclinical
United States
Alloy Therapeutics, Inc.
06 Jan 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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