Last update 01 Nov 2024

Anti-CEA CAR T cell therapy(Shanghai Genechem Co., Ltd.)

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
MG7-CART
Target
CEACAM5
Mechanism
CEACAM5 antagonists(Carcinoembryonic antigen related cell adhesion molecule 5 antagonists)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Liver CancerColorectal Cancer
Inactive Indication
Liver metastases
Originator Organization
Shanghai Genechem Co., Ltd.Shanghai Genechem Co., Ltd.
Active Organization
Shanghai Genechem Co., Ltd.Shanghai Genechem Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with Anti-CEA CAR T cell therapy(Shanghai Genechem Co., Ltd.)
NCT02862704 / Unknown statusPhase 1/2IIT
An Open-label, Uncontrolled, Single-arm Pilot Study to Evaluate Safety and Efficacy of Intratumoral Delivery Mediated MG7-targeted Chimeric Antigen Receptor T Cells in Advanced MG7 Positive Liver Metastases
100 Clinical Results associated with Anti-CEA CAR T cell therapy(Shanghai Genechem Co., Ltd.)
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100 Translational Medicine associated with Anti-CEA CAR T cell therapy(Shanghai Genechem Co., Ltd.)
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100 Patents (Medical) associated with Anti-CEA CAR T cell therapy(Shanghai Genechem Co., Ltd.)
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100 Deals associated with Anti-CEA CAR T cell therapy(Shanghai Genechem Co., Ltd.)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Liver metastasesPhase 2
CN
Shanghai Genechem Co., Ltd.Shanghai Genechem Co., Ltd.
01 Jun 2016
Liver CancerPhase 2
CN
Shanghai Genechem Co., Ltd.Shanghai Genechem Co., Ltd.
-
Colorectal CancerPhase 1
CN
Shanghai Genechem Co., Ltd.Shanghai Genechem Co., Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
AACR2018
Not Applicable
Metastatic colon cancer
-
rtmjettzqw(kpfioqkdlt) = During the treatment, the patient experienced cytokine release knpqafsndn (yqaporlczl )
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Positive
01 Jul 2018
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Approval

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Regulation

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