Last update 14 Jul 2025

Imipenem/Cilastatin Sodium/Funobactam

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
亚胺培南西司他丁钠福诺巴坦, 亚胺西福
Target
DPEP1 x PBPs x β-lactamase
Action
inhibitors
Mechanism
DPEP1 inhibitors(dipeptidase 1 inhibitors), PBPs inhibitors(Bacterial penicillin-binding protein inhibitors), β-lactamase inhibitors(Beta Lactamase inhibitors)
Therapeutic Areas
Infectious DiseasesUrogenital DiseasesRespiratory Diseases
Active Indication
Hospital acquired bacterial pneumoniaVentilator associated bacterial pneumoniaComplicated urinary tract infection
Inactive Indication-
Originator Organization
Evopoint Biosciences Co., Ltd.Evopoint Biosciences Co., Ltd.
Active Organization
Evopoint Biosciences Co., Ltd.Evopoint Biosciences Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseNDA/BLA
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC28H43N5NaO9S2
InChIKeyXWIKEETXNRMEDP-KJWPAVRRSA-N
CAS Registry85960-17-4

Related

1
Clinical Trials associated with Imipenem/Cilastatin Sodium/Funobactam
CTR20244156
/ CompletedPhase 1
健康受试者单次静脉输注福诺巴坦联合亚胺培南/西司他丁钠的随机、开放、两周期、两序列交叉的人体生物等效性研究
[Translation] A randomized, open-label, two-period, two-sequence crossover bioequivalence study of a single intravenous infusion of fonobactam combined with imipenem/cilastatin sodium in healthy subjects
100 Clinical Results associated with Imipenem/Cilastatin Sodium/Funobactam
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100 Translational Medicine associated with Imipenem/Cilastatin Sodium/Funobactam
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100 Patents (Medical) associated with Imipenem/Cilastatin Sodium/Funobactam
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100 Deals associated with Imipenem/Cilastatin Sodium/Funobactam
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hospital acquired bacterial pneumoniaNDA/BLA
China
Evopoint Biosciences Co., Ltd.Evopoint Biosciences Co., Ltd.
09 Jul 2025
Ventilator associated bacterial pneumoniaNDA/BLA
China
Evopoint Biosciences Co., Ltd.Evopoint Biosciences Co., Ltd.
09 Jul 2025
Complicated urinary tract infectionPhase 1
China
Evopoint Biosciences Co., Ltd.Evopoint Biosciences Co., Ltd.
14 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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