Last update 08 May 2025

TR115

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
EZH2
Action
inhibitors
Mechanism
EZH2 inhibitors(Histone-lysine N-methyltransferase EZH2 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
Non-Hodgkin's lymphoma refractoryRecurrent Non-Hodgkin LymphomaAdvanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Tarapeutics Science IncTarapeutics Science Inc
Active Organization
Tarapeutics Science IncTarapeutics Science Inc
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

3
Clinical Trials associated with TR115
CTR20251176
/ Active, not recruitingPhase 1
在中国健康受试者中评估食物对TR115片药代动力学特征影响的单中心、随机、开放、单次给药、两周期、双交叉研究
[Translation] A single-center, randomized, open-label, single-dose, two-period, double-crossover study to evaluate the effect of food on the pharmacokinetic characteristics of TR115 tablets in healthy Chinese subjects
NCT05650580
/ RecruitingPhase 1
A Phase I Clinical Study to Characterize Safety, Tolerability, and Pharmacokinetics of TR115 in Patients With Relapsed / Refractory Non-Hodgkin's Lymphoma or Advanced Solid Tumors
CTR20223220
/ RecruitingPhase 1
TR115片在复发/难治性非霍奇金淋巴瘤或晚期实体瘤患者的安全性、耐受性和药代动力学的Ⅰ期临床研究
[Translation] Phase I clinical study on the safety, tolerability and pharmacokinetics of TR115 tablets in patients with relapsed/refractory non-Hodgkin's lymphoma or advanced solid tumors
100 Clinical Results associated with TR115
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100 Translational Medicine associated with TR115
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100 Patents (Medical) associated with TR115
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100 Deals associated with TR115
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Hodgkin's lymphoma refractoryPhase 1
China
Tarapeutics Science IncTarapeutics Science Inc
23 Apr 2023
Recurrent Non-Hodgkin LymphomaPhase 1
China
Tarapeutics Science IncTarapeutics Science Inc
23 Apr 2023
Advanced Malignant Solid NeoplasmPhase 1
China
Tarapeutics Science IncTarapeutics Science Inc
17 Apr 2023
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Clinical Result

Indication
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Approval

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Regulation

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