Last update 23 Jan 2025

Mitiglinide Calcium Hydrate/Voglibose

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Glubes, Mitiglinide/voglibose, Voglibose/mitiglinide
+ [3]
Target
MGAM x Potassium channel x VGKCs
Mechanism
MGAM inhibitors(Maltase-glucoamylase inhibitors), Potassium channel blockers, VGKCs blockers(Voltage-gated potassium channel blockers)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication
Diabetes Mellitus, Type 2
Inactive Indication-
Originator Organization
Kissei Pharmaceutical Co., Ltd.Kissei Pharmaceutical Co., Ltd.
Active Organization
Kissei Pharmaceutical Co., Ltd.Kissei Pharmaceutical Co., Ltd.
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (22 Apr 2011),
Diabetes Mellitus, Type 2
Regulation-
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Structure/Sequence

Molecular FormulaC10H21NO7
InChIKeyFZNCGRZWXLXZSZ-CIQUZCHMSA-N
CAS Registry83480-29-9
View All Structures (2)

Related

5
Clinical Trials associated with Mitiglinide Calcium Hydrate/Voglibose
JPRN-UMIN000012294
/ CompletedNot ApplicableIIT
Clinical study on of combination therapy with a DPP-4 inhibitor and a mitiglinide/voglibose fixed-dose combination (the combination) on glycemic/metabolic responses after meals in patients with type 2 diabetic mellitus (T2DM) - Clinical study on combination therapy with a DPP-4 inhibitor and the combination in T2DM patients
JPRN-UMIN000011167
/ CompletedNot ApplicableIIT
Efficacy and safety of switching from thrice daily glinide or alpha-GI to twice daily mitiglinide/voglibose combined drug in type 2 diabetes. - Efficacy and safety of switching from thrice daily glinide or alpha-GI to twice daily mitiglinide/voglibose combined drug in type 2 diabetes.
JPRN-UMIN000008332
/ CompletedNot ApplicableIIT
Evaluation of effect of Glubes combination tablet on the HbA1c levels and vascular endothelial function - EGEF trial
100 Clinical Results associated with Mitiglinide Calcium Hydrate/Voglibose
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100 Translational Medicine associated with Mitiglinide Calcium Hydrate/Voglibose
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100 Patents (Medical) associated with Mitiglinide Calcium Hydrate/Voglibose
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100 Deals associated with Mitiglinide Calcium Hydrate/Voglibose
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External Link

KEGGWikiATCDrug Bank
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A10B
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
JP
Kissei Pharmaceutical Co., Ltd.Kissei Pharmaceutical Co., Ltd.
22 Apr 2011
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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