Last update 08 May 2025

PNU-159682-P1C1TM

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms-
Target
Top II x p53
Action
inhibitors
Mechanism
Top II inhibitors(Topoisomerase II inhibitors), p53 inhibitors(Tumor protein p53 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Neoplasms
Inactive Indication-
Originator Organization
Singapore Immunology NetworkSingapore Immunology Network
Active Organization
Singapore Immunology NetworkSingapore Immunology Network
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC32H35NO13
InChIKeySLURUCSFDHKXFR-WWMWMSKMSA-N
CAS Registry202350-68-3
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Related

100 Clinical Results associated with PNU-159682-P1C1TM
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100 Translational Medicine associated with PNU-159682-P1C1TM
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100 Patents (Medical) associated with PNU-159682-P1C1TM
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1
Literatures (Medical) associated with PNU-159682-P1C1TM
Nature CommunicationsQ1 · CROSS-FIELD
Targeting mutant p53-expressing tumours with a T cell receptor-like antibody specific for a wild-type antigen
Q1 · CROSS-FIELD
100 Deals associated with PNU-159682-P1C1TM
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical-
Singapore Immunology NetworkSingapore Immunology Network
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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