Last update 07 Feb 2026

AOC-1045

Overview

Basic Info

Drug Type
Antibody oligonucleotide conjugates
Synonyms
DMD exon 45(Avidity), AOC 1045, AOC1045
Target
DMD exon 45
Action
modulators
Mechanism
DMD exon 45 modulators(Dystrophin exon 45 modulators)
Therapeutic Areas
Nervous System DiseasesCongenital DisordersSkin and Musculoskeletal Diseases+ [1]
Active Indication
Muscular Dystrophy, Duchenne
Inactive Indication-
Originator Organization
Avidity Biosciences, Inc.Avidity Biosciences, Inc.
Active Organization
Avidity Biosciences, Inc.Avidity Biosciences, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with AOC-1045
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100 Translational Medicine associated with AOC-1045
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100 Patents (Medical) associated with AOC-1045
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100 Deals associated with AOC-1045
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Muscular Dystrophy, DuchennePreclinical
United States
Avidity Biosciences, Inc.Avidity Biosciences, Inc.
01 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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