Last update 20 Mar 2025

Hydroflumethiazide/Reserpine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Compound Reserpine and Hydrochlorthiazide, 氢氟噻嗪/利血平, SALUTENSIN-DEMI
+ [1]
Target
NCC x VMAT2
Action
inhibitors
Mechanism
NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors), VMAT2 inhibitors(Synaptic vesicular amine transporter inhibitors)
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Hypertension
Inactive Indication-
Originator Organization
Shire Pharmaceuticals Services Ltd.
Active Organization
Guangxi Nanning Baihui Pharmaceutical Group Co., LtdGuangxi Nanning Baihui Pharmaceutical Group Co., Ltd
Inactive Organization
Shire Development LLC
Drug Highest PhaseApproved
First Approval Date
United States (20 Jun 1960)
Regulation-
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Structure/Sequence

Molecular FormulaC33H40N2O9
InChIKeyQEVHRUUCFGRFIF-MDEJGZGSSA-N
CAS Registry50-55-5
View All Structures (2)

Related

100 Clinical Results associated with Hydroflumethiazide/Reserpine
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100 Translational Medicine associated with Hydroflumethiazide/Reserpine
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100 Patents (Medical) associated with Hydroflumethiazide/Reserpine
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2
Literatures (Medical) associated with Hydroflumethiazide/Reserpine
01 Feb 1970Current therapeutic research, clinical and experimental
A double-blind evaluation of the therapeutic efficacy of salutensin versus hydropres-50 in essential hypertension.
01 Sep 1959Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften
[Metabolic and clinic study of new non-mercurial diuretics].
100 Deals associated with Hydroflumethiazide/Reserpine
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External Link

KEGGWikiATCDrug Bank
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C02AA52C02LA01C03AH02
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
China
Guangxi Nanning Baihui Pharmaceutical Group Co., LtdGuangxi Nanning Baihui Pharmaceutical Group Co., Ltd
01 Jan 1982
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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