Novartis has scrapped a Phase II clinical trial of an investigational treatment for major depressive disorder related to suicidal ideation, the Swiss Big Pharma confirmed to
Endpoints News
.
The decision was made “following a benefit risk assessment of available data,” a Novartis spokesperson said via email. The cull was disclosed in an Oct. 6
update
to the federal trials database.
Novartis was testing MIJ821, an IV injection, versus placebo to see if it was better at reducing depression symptoms. The nearly 200-patient trial began in July 2021 and wrapped up this July, per the
clinicaltrials.gov
entry. The company secured the asset through its $210 million upfront
buyout of Cadent Therapeutics
in 2020.
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