[Translation] A Phase 3, multicenter, double-blind maintenance study to evaluate the long-term safety, tolerability, and efficacy of rocatinlimab in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD) (ROCKET-ASCEND)
一、主要目的:
描述Rocatinlimab在中度至重度AD受试者中的长期安全性和耐受性
二、次要目的:
在成人单药治疗研究的Rocatinlimab应答者中描述各个Rocatinlimab组与安慰剂相比的应答维持情况
评价Rocatinlimab 的免疫原性
研究Rocatinlimab 重复皮下给药后的药代动力学
[Translation] 1. Main purpose:
Characterizing the long-term safety and tolerability of rocatinlimab in subjects with moderate to severe AD
2. Secondary purpose:
Describing maintenance of response in each rocatinlimab arm compared with placebo among rocatinlimab responders in adult monotherapy studies
Evaluating the immunogenicity of rocatinlimab
Studying the pharmacokinetics of rocatinlimab following repeated subcutaneous administration