[Translation] A Phase III, 24-week, randomized, efficacy and safety study of BLU-5937 in an open-label, extended-treatment setting in adult subjects with refractory or unexplained chronic cough
主要目的:评估BLU-5937与安慰剂相比在基线24小时咳嗽频率≥8次咳嗽/小时的RCC(包括不明原因的慢性咳嗽)成人患者中对第24周时24小时咳嗽频率的影响以及确定截至第24周时BLU-5937与安慰剂相比在RCC(包括不明原因的慢性咳嗽)成人患者中的安全性 次要目的:评价BLU-5937对咳嗽频率和PRO等其他指标的影响 探索性目的:评价BLU-5937对咳嗽频率和PRO等其他指标的影响
[Translation] Primary Objectives: To evaluate the effect of BLU-5937 on 24-hour cough frequency at Week 24 compared to placebo in adult patients with RCC (including chronic cough of unknown etiology) with a baseline 24-hour cough frequency ≥8 coughs/hour and to determine the safety of BLU-5937 compared to placebo in adult patients with RCC (including chronic cough of unknown etiology) as of Week 24 Secondary Objectives: To evaluate the effect of BLU-5937 on other measures, including cough frequency and PROs Exploratory Objectives: To evaluate the effect of BLU-5937 on other measures, including cough frequency and PROs