Nanjing Youke Biomedical Research Co., Ltd.

To evaluate the efficacy and safety of sitafloxacin fumarate injection in the treatment of acute pyelonephritis/complicated urinary tract infection and to explore the optimal effective dose.

To evaluate the efficacy and safety of L-oxiracetam for injection in improving memory and intellectual impairment in patients with craniocerebral injury.

1) To evaluate the safety and tolerability of single and multiple administrations of sitafloxacin fumarate injection within a set dose range in healthy subjects; 2) To conduct a pharmacokinetic study of sitafloxacin fumarate injection in healthy subjects.