[Translation] A Phase IIb, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-finding study to evaluate the safety, tolerability, and efficacy of PQ912 in subjects with mild cognitive impairment and mild dementia due to Alzheimer's disease.
主要目的:
剂量选择的安全性
● 评估PQ912的安全性和耐受性
疗效
● 评价PQ912对工作记忆和注意力的作用
次要目的
安全性
● 评估PQ912的长期安全性和耐受性
疗效
● 评价PQ912对脑活动 (EEG) 的作用
● 评价PQ912对认知的作用
● 评价PQ912对日常生活能力的作用
[Translation] Primary objectives:
Safety of dose selection
● Evaluate the safety and tolerability of PQ912
Efficacy
● Evaluate the effect of PQ912 on working memory and attention
Secondary objectives
Safety
● Evaluate the long-term safety and tolerability of PQ912
Efficacy
● Evaluate the effect of PQ912 on brain activity (EEG)
● Evaluate the effect of PQ912 on cognition
● Evaluate the effect of PQ912 on daily living ability