Shaanxi University of Technology

Dynamic cancer control is a current health system priority, yet methods for achieving it are lacking. This study aims to review the application of system dynamics modeling (SDM) on cancer control and evaluate the research quality.

Articles were searched in PubMed, Web of Science, and Scopus from the inception of the study to 15 November 2023. Inclusion criteria were English original studies focusing on cancer control with SDM methodology, including prevention, early detection, diagnosis and treatment, and palliative care. Exclusion criteria were non-original research, and studies lacking SDM focus. Analysis involved categorization of studies and extraction of relevant data to answer the research question, ensuring a comprehensive synthesis of the field. Quality assessment was used to evaluate the SDM for cancer control.

Sixteen studies were included in this systematic review predominantly from the United States (7, 43.75%), with a focus on breast cancer research (5, 31.25%). Studies were categorized by WHO cancer control modules, and some studies may contribute to multiple modules. The results showed that included studies comprised two focused on prevention (1.25%), ten on early detection (62.50%), six on diagnosis and treatment (37.50%), with none addressing palliative care. Seven studies presented a complete SDM process, among which nine developed causal loop diagrams for conceptual models, ten utilized stock-flow charts to develop computational models, and thirteen conducted simulations.

This review's macrofocus on SDM in cancer control missed detailed methodological analysis. The limited number of studies and lack of stage-specific intervention comparisons limit comprehensiveness. Detailed analysis of SDM construction was also not conducted, potentially overlooking nuances in cancer control strategies.

SDM in cancer control is underutilized, focusing mainly on early detection and treatment. Inconsistencies suggest a need for standardized SDM approaches. Future research should expand SDM's application and integrate it into cancer control strategies.

In this paper, LiF and HCl were used to etch Ti₃AlC₂ to obtain MXene; Then, g-C₃N₄ and triazole were utilized to resp. modify MXene to obtain the hybrid g-C₃N₄/MXene (GM) and triazole/MXene (TM) composites.Morphologies, adsorption kinetics and thermodn., recycling and green plant cultivating, bactericidal properties, and the mechanism for absorption and bactericidal of MXene, GM, and TM were sufficiently presented.Compared to the MXene, the interlayer spacing of the TM and GM are exfoliated more perfectly with more active sites and excellent adsorption performance of the GM and TM composites for methylene blue (MB) from 47.48 mg/g to 866.86 mg/g and 340.26 mg/g.Importantly, with the incorporation of triazole, the adsorption performance and adsorption range of the TM are significantly improved, and more than 90 % MB removal could be achieved at pH of 2-10, which is much higher than that of most of the adsorbents reported in the previous studies.Moreover, according to DFT calculations of the GM and TM, it can be concluded that the binding energies of MXene, GM, and TM composites for MB are -9.53 Kcal/mol, -66.14 Kcal/mol and -55.51 Kcal/mol, resp.Furthermore, the bacteriostatic performance test shows that both GM and TM could enhance the bacteriostatic capacity of MXene, and the bacteriostatic performance of TM is more prominent owing to the effect of triazole.This work not only explores the modification method for the outstanding adsorption and bacteriostatic performance of hybrid MXene composites but also broadens the functional application scope of MXene-based composites, which provides novel ideas for the application of MXene-based composites in wastewater treatment.

Tremor is a rhythmic, involuntary oscillatory movement that severely affects some aspects of a patient's daily life. The use of wearable tremor-suppressing orthoses has become an effective, noninvasive treatment method for controlling tremors. This article summarizes recent developments in upper limb tremor suppression orthoses, aiming to provide a foundation for future research. By analyzing the working mechanisms, degrees-of-freedom (DOFs), weight, and tremor suppression effectiveness of various types of orthoses, the following conclusions are drawn: We found that differences in the working mechanism and the number of suppression directions are related to the weight of the device; weight, in turn, is a major factor affecting the comfort of the orthoses; and the combination of the number and weight of the damping direction affects the effect of the damping equipment. Balancing these three factors should be a key focus of future research. Moreover, researchers are placing greater emphasis on the comfort of the wearer during the development of these orthoses.