特瑞普利单抗联合贝伐珠单抗对比索拉非尼一线治疗晚期肝细胞癌的安全性和有效性的随机、开放、多中心III期研究
[Translation] A randomized, open-label, multicenter phase III study on the safety and efficacy of toripalimab combined with bevacizumab versus sorafenib as first-line treatment for advanced hepatocellular carcinoma
比较特瑞普利单抗联合贝伐珠单抗与索拉非尼一线治疗晚期肝细胞癌的总生存期(OS) 及由独立影像评审委员会根据RECIST v1.1标准评估的无进展生存期(PFS)。
[Translation] To compare the overall survival (OS) and progression-free survival (PFS) assessed by an independent imaging review committee according to RECIST v1.1 criteria between toripalimab plus bevacizumab and sorafenib as first-line treatment for advanced hepatocellular carcinoma.
特瑞普利单抗联合仑伐替尼对比仑伐替尼单药一线治疗晚期肝细胞癌前瞻性随机对照双盲多中心III期临床研究
[Translation] A prospective, randomized, controlled, double-blind, multicenter phase III clinical study of toripalimab combined with lenvatinib versus lenvatinib alone as the first-line treatment for advanced hepatocellular carcinoma
旨在评价特瑞普利单抗联合仑伐替尼(试验组)对比安慰剂联合仑伐替尼(对照组)一线治疗晚期肝细胞癌(HCC)受试者的有效性和安全性,以及免疫原性、药代动力学和药效学特征。
[Translation] To evaluate the efficacy and safety of toripalimab combined with lenvatinib (experimental group) versus placebo combined with lenvatinib (control group) in the first-line treatment of subjects with advanced hepatocellular carcinoma (HCC), as well as the immunogenicity, pharmacokinetic and pharmacodynamic characteristics.
特瑞普利单抗联合含铂双药化疗用于可手术IIIA期非小细胞肺癌受试者的随机、双盲、安慰剂对照、多中心III期临床研究
[Translation] A randomized, double-blind, placebo-controlled, multicenter phase III clinical study of toripalimab combined with platinum-based doublet chemotherapy in patients with operable stage IIIA non-small cell lung cancer
比较新辅助特瑞普利单抗联合含铂双药化疗对比安慰剂联合含铂双药化疗治疗可手术IIIA期非小细胞肺癌(NSCLC)受试者的主要病理学缓解率(MPR率)(根据盲态独立中心病理(BIPR)评估)。
[Translation] To compare the major pathological response rate (MPR rate) of neoadjuvant toripalimab plus platinum-doublet chemotherapy versus placebo plus platinum-doublet chemotherapy in subjects with operable stage IIIA non-small cell lung cancer (NSCLC) according to blinded independent central pathology (BIPR) assessment.
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