Delving into the Latest Updates on Nanjing Lifenergy R&D Co., Ltd. with Synapse

Overview

A review.3-Me-2-oxo-butanoic acid was a kind of bifunctional compound with special and active nature.It was an important intermediate for drug synthesis and biol. transformation.And its calcium salt, as an effective drug, was used to treat urinary disease for many years.The main synthesis methods of 3-Me-2-oxo-butanoic acid were reviewed.Combining technol. features, a detailed comparative anal. of preparation methods, suitable for industrial production, was supplied.

Yaowu Shengwu Jishu

Determination of emodin in Gongliuqing tablets by HPLC

Author: Liu, Sai ; Zha, Jing ; Xiong, Shoujun

To establish a HPLC method for determination of emodin in Gongliuqing tablets, the chromatog. column of Merck C₁₈ (150 mm*4.6 mm) was used.The mobile phase consisted of methanol-0.1% phosphoric acid (75:25) and the flow rate was 1.0 mL/min.The detection wavelength was set at 286 nm.The linear response range was 4.09-14.31μg/mL (r = 0.9999).The mean recovery was 100.5% (RSD=1.36%).This method was simple, rapid and accurate.So it was suitable for determination of emodin in Gongliuqing tablets.

Zhongguo Yiyuan Yaoxue Zazhi

Stability of ibuprofen injection combined with commonly used infusions

Author: Shi, Cun-yuan ; Wu, Jun ; Wu, Chang-xuan

Stability of ibuprofen injection combined with 0.9% sodium chloride injection and 5% glucose injection was explored, the final dilution concentration of ibuprofen was 4 mg·mL^-1, 2 mg·mL^-1 and 1 mg·mL^-1.Solution clarity, pH and ibuprofen level change in 24 h was observed and analyzed.When arginine-ibuprofen infection (0.92: 1.00) combined with 0.9% sodium chloride injection with final ibuprofen concentration of 4 mg·mL^-1 and 1 mg·mL^-1 or combined with 5% glucose infection with final concentration of 4 mg·mL^-1, 2 mg·mL^-1 and 1 mg·mL^-1, the solution became turbid.When arginine-ibuprofen infection (1.01: 1.00) combined with 0.9% sodium chloride injection/5% glucose infection with final ibuprofen concentration of 4 mg·mL^-1 and 1 mg·mL^-1, the solution was clear in 24 h, and pH and ibuprofen content didn't changed significantly.Arginine-ibuprofen infection (1.01: 1.00) combined with 0.9% sodium chloride injection/5% glucose infection with final ibuprofen concentration of 4 mg·mL^-1 and 1 mg·mL^-1 is stable in 24 h in room temperature

100 Deals associated with Nanjing Lifenergy R&D Co., Ltd.

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100 Translational Medicine associated with Nanjing Lifenergy R&D Co., Ltd.

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Pipeline

Pipeline Snapshot as of 24 Jan 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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