Delving into the Latest Updates on Glatt Air Techniques, Inc. with Synapse

Overview

本研究的主要目的是： -在中国健康受试者中描述ANJ900 单次口服给药的药代动力学（PK）特征 -在中国健康受试者中评价食物对 ANJ900 单次口服给药PK 的影响本研究的次要目的是： - 在中国健康受试者中比较 ANJ900 与二甲双胍速释（IR）片的PK ？评估 ANJ900 在中国健康受试者中的安全性和耐受性

[Translation]

The primary objectives of this study are: - To characterize the pharmacokinetic (PK) characteristics of a single oral dose of ANJ900 in healthy Chinese subjects - To evaluate the effect of food on the PK of a single oral dose of ANJ900 in healthy Chinese subjects The secondary objectives of this study are: - To compare the PK of ANJ900 with metformin immediate-release (IR) tablets in healthy Chinese subjects ? To evaluate the safety and tolerability of ANJ900 in healthy Chinese subjects

Start Date15 Oct 2021

Sponsor / Collaborator

Anji Pharmaceuticals (Shanghai) Co., Ltd.

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100 Clinical Results associated with Glatt Air Techniques, Inc.

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0 Patents (Medical) associated with Glatt Air Techniques, Inc.

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8

Literatures (Medical) associated with Glatt Air Techniques, Inc.

19 May 1994·Drugs and the Pharmaceutical Sciences

Formulation and Process Considerations

Author: Jones, David M. ; Percel, Phillip J.

A review with 17 references

Development, optimization, and scale-up of process parameters: wurster coating

Author: Godek, E. ; Jones, D.

A review.This article discusses about Wurster process which is used commercialiy for coating particles from less than 100 nm to tablets, and for layering to produce core materials.The Wurster process is used com. for coating and layering.Substrates include particles smaller than 100μ, crystals, granules, pellets, and tablets.The films may be applied using water-based solutions, aqueous dispersions, or organic solvents.It is also possible to apply coatings via hot-melt, but the use of the Wurster system for this technique may be related more to the particle size of the substrate than the coating process itself.The working capacity for a Wurster insert of a particular size is generally defined as the volume outside of the partition, with the partition at rest on the orifice plate.Avoiding loading of product inside the partition helps to ensure that the nozzle remains clear at the beginning of the process.Irresp. of the amount of substrate in the Wurster insert, the fluidization pattern is controlled by the orifice plate configuration, the partition height, and the fluidization air volumeEvaporation rate or drying capacity is controlled by fluidization air volume, temperature, and its absolute humidity (dew point).The temperature of the fluidization air is generally adjusted to maintain a constant product temperatureThe product temperature, in turn, is influenced by spray rate, and humidity of the incoming air.

Adjustable capsule release by use of 2-phase coatings

Author: Stamato, Howard J.

Fluid-based application of two phase systems is a simple and effective means of providing specialized microcapsules.The two phase nature of the coatings allows the creation of a porous membrane surrounding the dissolving core.Using this system most effectively, the continuous component of the coating can be chosen for ease of processing conditions allowing the choice of the second dispersed component to be made with the release profile instead of the ability to apply coating as the major consideration.A wide range of release behavior should be possible by taking advantage of this freedom.Addnly. the pore size may be controlled by the size of the solids or emulsion droplets of the second phase.This technique could provide an easily adjustable way to control the release mechanism.The constant surface area of the diffusion envelope during the dissolving process is an added benefit stabilizing the release profile.

100 Deals associated with Glatt Air Techniques, Inc.

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100 Translational Medicine associated with Glatt Air Techniques, Inc.

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