Delving into the Latest Updates on Angelini Farmaceutica SA with Synapse

Overview

Tetrahydrozoline, naphazoline, xylometazoline, and oxymetazoline, present in nasal and eye drops, were determined by gas chromatog., using FFAP polar stationary phase which has high thermal stability.No failing was observed with this phase material, and the method is precise and accurate.Compounds such as neomycin, hydrocortisone, benzalhonium chloride, and menthol did not interfere with the determination

Farmaco

Indirect UV detection in HPLC determination of UV-transparent non-electrolytes in pharmaceutical dosage forms

Author: Massaccesi, Maurizio

After briefly reporting the basic concepts of indirect UV detection in HPLC, methods for the quant. determination of ethanol, glycerol and isopropanol in pharmaceutical forms for human use, and propylene glycol and N,N-dimethylacetamide in pharmaceutical form for veterinary use are proposed.Nicotinamide, sulfanilamide and isoniazid are used as UV-absorbing components (probes) of mobile phase.The last two are new probes suitably selected and proposed to optimize the determinationAlso, the dependence of method sensitivity from the probe concentration is shown.Good accuracies and precisions are obtained.The methods are simple and quick and the assays of the analytes do not go through interferences from the other substances present in the pharmaceutical forms.

Farmaco, Edizione Pratica

Heterogeneous-phase titration of imidazolines in pharmaceuticals

Author: Massaccesi, M.

Tetrahydrozoline [84-22-0], naphazoline [835-31-4], xylometazoline [526-36-3], antazoline [91-75-8], and oxymetazoline [1491-59-4] were determined in a mixture of CH₂Cl₂ and pH 6.88 phosphate buffer by titration with 0.01M Na dioctylsulfosuccinate by using tetrabromophenophthalein Et ester K salt as indicator.The relative standard deviation was 0.29-0.32%.

100 Deals associated with Angelini Farmaceutica SA

Login to view more data

100 Translational Medicine associated with Angelini Farmaceutica SA

Login to view more data