[Translation] A single-center, randomized, open-label, single- and multiple-in-human pharmacokinetics trial of levosulpiride injection in healthy Chinese subjects
健康受试者进行左舒必利注射液的药代动力学试验,测定主要成分左舒必利的经时血药浓度,估算其主要药代动力学参数,了解左舒必利注射液在健康人体内的吸收、分布、消除、代谢规律,为制定左舒必利注射液II期临床试验方案提供试验依据,为临床用药的给药剂量提供依据。
[Translation] The pharmacokinetics test of levosulpiride injection was performed on healthy subjects, the blood concentration of the main component levosulpiride was measured over time, its main pharmacokinetic parameters were estimated, and the absorption and distribution of levosulpiride injection in healthy subjects were known. , Elimination and metabolism laws, provide experimental basis for the formulation of the Phase II clinical trial plan of levosulpiride injection, and provide the basis for the dosage of clinical medication.