Hennepin County Medical Center

BETHESDA, Md., March 16, 2023 /PRNewswire/ -- Nancy J. Mendelsohn, MD, FACMG has been elected as president of the ACMG Foundation for Genetic and Genomic Medicine. The ACMG Foundation is a national nonprofit foundation dedicated to improving health and patient care through the support of research, education and the safe, effective practice of genetic and genomic medicine. Dr. Mendelsohn, previously a member of the Foundation's board of directors, is the fourth person and first woman to serve as the organization's president. She succeeds Bruce R. Korf, MD, PhD, FACMG, who is stepping down on March 18, 2023 after 11 years at the Foundation's helm. "It has been a great joy to have served alongside of Dr. Mendelsohn as a Foundation Board member and I welcome her into this new role as president of the Foundation with unbridled enthusiasm and a sense of great expectation," said Robert G. Best, PhD, FACMG, interim chief executive officer of the American College of Medical Genetics and Genomics (ACMG) and the ACMG Foundation. "Nancy brings a wealth of knowledge and fresh perspective as a top executive leader with a deep understanding of the payor landscape, a seasoned clinical geneticist with particular mastery in the treatment of lysosomal storage disorders, an accomplished scholar and a person with longstanding commitments to governance within medical genetics as evidenced by her notable service to the College, Foundation, and our certifying board, the American Board of Medical Genetics and Genomics (ABMGG)." "I am delighted that Dr. Nancy Mendelsohn will succeed me as president of the ACMG Foundation. Dr. Mendelsohn is an accomplished medical geneticist with broad experience both in clinical practice and the administration and management of medical genetics services. She has been an outstanding member of the Foundation Board of Directors and will be an outstanding spokesperson for the Foundation and our field as president," said ACMG Foundation President Bruce R. Korf, MD, PhD, FACMG. Previously the chief medical officer for Complex Health Solutions at UnitedHealthcare and a clinical leader serving in both the Optum and UnitedHealth Group organizations, Dr. Mendelsohn is a clinical geneticist, physician-scientist, healthcare executive and researcher with leadership experience. Her role as chief of specialty pediatrics at Children's Minnesota, one of the largest children's hospital centers in the United States, included the strategy and development of the multi-specialty physician practice. She has more than 50 peer-reviewed publications, book chapters and presentations. Dr. Mendelsohn received a Bachelor of Science in Molecular Biology from Indiana University and an MD from the University of Missouri. She completed a residency in pediatrics and a fellowship in medical genetics at St. Louis Children's Hospital at Washington University in St. Louis, Missouri. Early on as a general pediatrician and an Assistant Professor, Division of Medical Genetics, Department of Pediatrics, at the University of Minnesota Medical School, she established the first genetics service at Hennepin County Medical Center. Dr. Mendelsohn then would go on to build the genetics program at Gillette Children's Specialty Healthcare and Children's Hospital Minnesota from as little as two clinicians to the largest genetics program in the upper Midwest. She has served broadly on national committees for the American Academy of Pediatrics (AAP), the ACMG, the ABMGG, and Children's Minnesota. "It is truly an honor to be elected by my peers to serve as president of the ACMG Foundation and I am humbled and privileged to follow the Foundation's three previous leaders: David L. Rimoin, MD, PhD, R. Rodney Howell, MD, FACMG and Dr. Bruce Korf. It is exciting to be elected at a time when the field of genetics and genomics is rapidly expanding and integral to clinical medicine," noted Dr. Mendelsohn. "As a believer in servant leadership, I am hopeful I can support the Foundation as we continue its role and grow, finding new ways to broaden our community and further the College's mission. I look forward to getting to know the members of the ACMG Foundation staff, the leadership of the Board and Foundation better, and to meeting many others in our community." About the ACMG Foundation for Genetic and Genomic Medicine The ACMG Foundation for Genetic and Genomic Medicine, a 501(c)(3) nonprofit organization, is a community of supporters and contributors who understand the importance of medical genetics and genomics in healthcare. Established in 1992, the ACMG Foundation supports the American College of Medical Genetics and Genomics (ACMG) mission to "translate genes into health." Through its work, the ACMG Foundation fosters charitable giving, promotes training opportunities to attract future medical geneticists and genetic counselors to the field, shares information about medical genetics and genomics, and sponsors important research. To learn more and support the ACMG Foundation mission to create "Better Health through Genetics" visit Barry Eisenberg, MS [email protected] SOURCE American College of Medical Genetics and Genomics

LAS VEGAS, March 9, 2023 /PRNewswire/ -- The American Academy of Orthopaedic Surgeons (AAOS) presented its 2023 William W. Tipton Jr., MD, Leadership Award to Alex Jahangir, MD, FAAOS. The Tipton Leadership Award recognizes AAOS members who have demonstrated outstanding leadership qualities that have benefitted the orthopaedic community, patients and/or the American public. The award honors and celebrates the life, accomplishments and qualities of the late William W. Tipton Jr., MD, an orthopaedic surgeon, educator and former AAOS chief executive officer. "The greatest honor of my professional career is receiving the William W. Tipton Jr. Leadership Award. Ours is a specialty that disproportionately produces many leaders in our practices, our communities and our nation. I am extremely humbled to be recognized as a Tipton honoree when so many other leaders in orthopaedics are equally deserving," Dr. Jahangir said. Inspiring community action Dr. Jahangir, a professor and vice chair of the Department of Orthopaedic Surgery at Vanderbilt University Medical Center (VUMC) in Nashville, Tenn., has not only made an impact in the field of orthopaedic surgery through his practice, but has also made a lasting impression on his community by simultaneously heading the Nashville COVID-19 task force during the height of the pandemic. While serving as chair of the Metropolitan Board of Health Nashville, Dr. Jahangir was named chair of the Metropolitan Nashville COVID-19 Taskforce by Mayor John Cooper. He remained in that role for two years, while simultaneously continuing his practice at VUMC. Throughout his service on the task force, Dr. Jahangir implemented new policies and practices that helped better protect public health, including establishing city-wide COVID-19 testing and vaccination services. According to William T. Obremskey, MD, FAAOS, professor of orthopaedic surgery at Vanderbilt, "One of Dr. Jahangir's most significant collaborative initiatives was his work early in 2021 with Nashville's three major tertiary medical centers — VUMC, HCA Healthcare/TriStar Division and Ascension Saint Thomas — to develop the state's first-ever regional transfer coordinating center between these three friendly, but fierce competitors." Established in January 2021, the Middle Tennessee Transfer Coordination Center was designed to help regional hospitals around Nashville manage bed shortages due to the pandemic and seamlessly transfer patients to larger facilities as needed. "As a result of Dr. Jahangir's team-building efforts, not one resident had to seek inpatient care outside of middle Tennessee — even as the Delta and Omicron variants raged — which undoubtedly saved countless lives," Dr. Obremskey said. Leading by example Dr. Jahangir immigrated from Iran to Nashville as a child in the 1980s. His father also practiced medicine in Nashville at Meharry Medical College, American's largest historically Black medical school. Dr. Jahangir attended the University of Tennessee for medical school, and completed his orthopaedic surgery residency at the Campbell Clinic in Memphis, Tenn. He then completed an orthopaedic trauma fellowship at Hennepin County Medical Center in Minneapolis, Minn. Dr. Jahangir has a track record of investing his time and energy into the city of Nashville and the state of Tennessee. He serves on the boards of several organizations working to improve the lives of Tennesseans, including the Nashville Convention & Visitors Corporation, Center for Nonprofit Management, NashvilleHealth, and the University School of Nashville. He is highly recognized and awarded by his community. Among his honors are the Nashville Chamber of Commerce's Spirit of the Region Award; the Nashville Public Education Foundation Distinguished Alumni Award; the St. Jude Children's Research Hospital Spirt of the Dream Award; and VUMC's 5 Pillar Award. The Nashville Business Journal named Dr. Jahangir to its Power 100 list in 2020, 2021 and 2022. "As both an orthopaedic and civic leader, Dr. Jahangir continues to guide teams of all shapes and sizes to make lasting impacts on countless lives. He has taken the fundamental characteristics that define a successful orthopaedic surgeon — to think fast, build trust and make order out of chaos — and brought them out into the larger world," Dr. Obremskey said. After receiving the award at the AAOS 2023 Annual Meeting in Las Vegas, Dr. Jahangir said: "I am keenly aware that I have been able to make contributions to my profession, institution and community because of the generous support of many mentors and colleagues who have encouraged me throughout my orthopaedic career. I am committed to embodying the high standards of leadership that our profession demands." About the AAOS With more than 39,000 members, the American Academy of Orthopaedic Surgeons is the world's largest medical association of musculoskeletal specialists. The AAOS is the trusted leader in advancing musculoskeletal health. It provides the highest quality, most comprehensive education to help orthopaedic surgeons and allied health professionals at every career level to best treat patients in their daily practices. The AAOS is the source for information on bone and joint conditions, treatments and related musculoskeletal healthcare issues; and it leads the healthcare discussion on advancing quality. Follow the AAOS on Facebook, Twitter, LinkedIn and Instagram. View original content to download multimedia: SOURCE American Academy of Orthopaedic Surgeons

ROSEMONT, Ill., Feb. 10, 2023 /PRNewswire/ -- The 2023 Kappa Delta Elizabeth Winston Lanier Award was presented to the Major Extremity Trauma Research Consortium (METRC) for its multi-disciplinary research platform addressing the challenging issues related to the evaluation, treatment and recovery after severe extremity trauma. This award recognizes research in musculoskeletal disease or injury with great potential to advance patient care. As the largest orthopaedic trauma research enterprise to date, METRC has conducted 34 studies, enrolled over 22,000 patients across 70 sites and published 57 papers, resulting in increased awareness and funding for extremity trauma care. Continue Reading The 2023 Kappa Delta Elizabeth Winston Lanier Award was presented to the Major Extremity Trauma Research Consortium for its multi-disciplinary research platform addressing the challenging issues related to the evaluation, treatment and recovery after severe extremity trauma. To read more about the award, please click here. Highlights from the Research During Operation Iraqi Freedom and Operation Enduring Freedom in Afghanistan, military orthopaedic surgeons were challenged with a surge of casualties with complex single or multiple extremity injures. While advanced field care and the use of body armor reduced combat mortality, it increased the injury burden to the unprotected extremities. Critical challenges surfaced, including complex wound management, infection, bone and articular surface loss, blast-related heterotopic ossification, segmental nerve injury, volumetric muscle loss, acute compartment syndrome (ACS) and severe psychological stress that can complicate long-term recovery. At the same time, surgeons at Level I trauma centers across the country were experiencing similar challenges for treating civilian patients with high energy traumas, such as severe leg injuries with open fractures, bone loss, muscle and nerve damage, heavy contamination and compartment syndrome. With lobbying support from the American Academy of Orthopaedic Surgeons (AAOS), the Department of Defense (DOD) requested proposals for an inaugural peer-reviewed consortium grant for Extremity War Injury research in 2008. Rather than submit competing applications, existing trauma research teams from the Lower Extremity Assessment Project (LEAP) study, the Southeast Fracture Consortium and the Orthopaedic Trauma Research Consortium worked together to develop an inclusive and unified approach, assembling top talent from around the country. As a result, METRC was formed, and in 2009 was awarded the DOD grant to establish a clinical research platform infrastructure and initiate prospective clinical research targeted to infection, ACS and bone healing. "By establishing a military-civilian research collaboration, investigators could translate learnings across sectors, research could continue during interwar periods and the research dollars could benefit from an economy of scale by sharing resources and reducing the cost per study, while increasing productivity," said Michael J. Bosse, MD, FAAOS, clinical chair emeritus of METRC. METRC was anchored by a Data Coordinating Center at the Johns Hopkins Bloomberg School of Public Health and initially engaged clinical investigators at 20 Level I trauma centers and the four major military treatment facilities. The success of the Consortium can be attributed to the following framework: Conducting randomized clinical trials and employing a "gaps driven" approach to define research that purposefully identifies challenging surgical and scientific questions Organizing a multi-center approach to conduct timely and clinically impactful research Developing a coordinated, standardized approach to protocol development and data collection Understanding that METRC's growth allows for the design and execution of large pragmatic trials Establishing quality assessment and improvement strategies to learn, evolve and improve from each study Supporting individual participating investigators and academic centers to receive extremity trauma research funding "We knew this initiative would not be successful unless we adopted a culture of collaboration among the researchers at our institutions," said Ellen J. MacKenzie, PhD, METRC founding director of the Coordinating Center. "We worked hard to develop processes that were engaging, made everybody feel included, gave everybody a voice and recognized the collective accomplishments of the team." METRC selected seven research areas that were thought to be of highest importance in both military and civilian high energy trauma patients. These included: Prevention and management of acute and chronic musculoskeletal infections Early acute management of orthopaedic injury Reconstruction surgery and nonsurgical management to improve bone healing Prediction, prevention and amelioration of secondary conditions and long-term physical health effects Management of pain and psychosocial sequelae Rehabilitation interventions to improve functional outcomes and quality of life Amputation and limb salvage outcomes including optimization of prosthetics and orthotic devices The Consortium's research findings include: The Prevent CLOT study, the largest of the METRC research efforts, enrolled over 12,000 patients and showed that low dose aspirin was non-inferior to low-molecular-weight heparin in preventing death and was associated with a low incidence of deep-vein thrombosis and pulmonary embolism in the care of trauma patients with operatively treated extremity fractures or with any pelvic or acetabular fractures.i The VANCO studyii,iii investigated an emerging low-cost topical wound antibiotic technique to reduce fracture-related infections by applying 1,000 mg of topical vancomycin to the wound prior to closure. The study demonstrated a 35% overall reduced risk of infection and a 50% reduction in gram positive infections. A study involving tobramycin targeting gram negative bacteria is currently underway. The Predicting Acute Compartment Syndrome studyiii sought to gain a better understanding of diagnostic standards for ACS, a challenging condition, as it is difficult to diagnose, can occur quickly and potentially lead to amputation or death. While more research is needed, in this study, near-infrared spectroscopy was unreliable for continuous measurement of tissue oxygenation in limbs with tibia fracturesiv and was not able to reliably identify early changes in tissue oxygenation in patients at risk for ACS. Additionally, using a novel approach of having an expert panel review each case to determine whether ACS was present, the research highlighted a high incidence of unnecessary surgery when using a currently accepted standard of care to determine when fasciotomy is necessary (a surgery that is done emergently to reduce muscle pressure to maintain blood flow)v. The OUTLET study provided further analysis of the 2002 LEAP study cohort, which originally found that limb salvage and amputation provided similar outcomes for severe high energy trauma below the distal femur. Following reports of disappointing results from the salvage attempts of those patients with a severely injured distal tibia, ankle and/or foot, the OUTLET study found that for a subset of those with severe and complex foot and ankle injuries, early amputation was associated with a better outcome than the limb salvage patientsvi. "Over the past decade, the Consortium has grown to over 400 investigators, and what's really impressive is the caliber of those who are involved," said Dr. Bosse. "They are the who's who in orthopaedic trauma in North America. Not only are they making game-changing discoveries, but they are training the next generation of residents, fellows and investigators, many of whom have gone on to start METRC-funded research centers." Since 2009, METRC has received $150 million in funding from the DOD, Patient Centered Outcomes Research Institute and National Institutes of Health. "The real advantage of the Consortium has been the ability to leverage our resources across studies, which otherwise couldn't have been conducted had it not been for the large multi-disciplinary team spanning numerous leading trauma centers across the country," said Dr. MacKenzie. "The funding has helped us maintain the infrastructure at the coordinating center and clinical sites to conduct this research, and a continued investment will not only advance the care of injured service members in future conflicts but contribute to the medical readiness of current forces." About the Kappa Delta Awards In 1947, at its golden anniversary, the Kappa Delta Sorority established the Kappa Delta Research Fellowship in Orthopaedics, the first award ever created to honor achievements in the field of orthopaedic research. The first annual award, a single stipend of $1,000, was made available to the AAOS in 1949 and presented at the AAOS meeting in 1950. The Kappa Delta Awards have been presented by the AAOS to persons who have performed research in orthopaedic surgery that is of high significance and impact. The sorority has since added two more awards and increased the award amounts to $20,000 each. Two awards are named for the sorority national past presidents who were instrumental in the creation of the awards: Elizabeth Winston Lanier, and Ann Doner Vaughn. The third is known as the Young Investigator Award. For more information about the manuscript submission process, please visit aaos.org/kappadelta. Learn more about the Kappa Delta Foundation, here. About the AAOS With more than 39,000 members, the American Academy of Orthopaedic Surgeons is the world's largest medical association of musculoskeletal specialists. The AAOS is the trusted leader in advancing musculoskeletal health. It provides the highest quality, most comprehensive education to help orthopaedic surgeons and allied health professionals at every career level to best treat patients in their daily practices. The AAOS is the source for information on bone and joint conditions, treatments and related musculoskeletal healthcare issues and it leads the healthcare discussion on advancing quality. Follow the AAOS on Facebook, Twitter, LinkedIn and Instagram. Disclosure Funding and Conflicts of Interest METRC has no conflicts of interests. METRC Grants, Award Numbers, Prime Award Recipients: DoD Consortium Award METRC 1, W81XWH-09-2-0108, Johns Hopkins Bloomberg School of Public Health METRC 2, W81XWH-10-2-0090, Johns Hopkins Bloomberg School of Public Health METRC 3, W81XWH-16-2-0060, Johns Hopkins Bloomberg School of Public Health DoD PRORP SEXTANT, W81XWH-19-2-0062, Carolinas Medical Center Stem Cell, W81XWH-18-2-0055, Johns Hopkins School of Medicine TOBRA, W81XWH-19-1-0848, University of Maryland UNION Biomarkers, W81XWH-19-1-0796, Boston Medical Center VANCO, W81XWH-10-2-0134, University of Maryland Weight Bearing, W81XWH-18-1-0810, Vanderbilt University Medical Center Mobility Tool Kit, W81XWH-18-1-0815, Carolinas Medical Center OXYGEN, W81XWH-12-1-0588, University of Maryland POvIV, W81XWH-10-2-0133, Vanderbilt University Medical Center POvIV II, TBD, Vanderbilt University Medical Center PACS II, W81XWH-20-2-0050, Hennepin County Medical Center PACS-PH, TBD, Hennepin County Medical Center METALS II, W81XWH-15-2-0058, Johns Hopkins Bloomberg School of Public Health NERVE, W81XWH-15-2-0074, Johns Hopkins School of Medicine ProFit; W81XWH-14-1-0563, University of California San Francisco PRIORITI – MTF, W81XWH-12-2-0032, Johns Hopkins Bloomberg School of Public Health REPAIR, W81XWH-15-2-0067, Johns Hopkins Bloomberg School of Public Health NSAIDS, W81XWH-20-2-0063, University of Utah DoD AFIRM Peg Fusion, W81XWH-20-1-0825, Johns Hopkins School of Medicine NIH-NIAMS STREAM, R01AR064066, Johns Hopkins Bloomberg School of Public Health PCORI Prevent Clot, PCS-1511-32745, University of Maryland School of Medicine i METRC. Aspirin or low-molecular-weight heparin for thromboprophylaxis after fracture. N Engl J Med 2023;388:203-13. ii Bosse, M.J., MacKenzie, E.J., Pollak, A.N., Stinner, D.J. (Eds). 2017. The Major Extremity Trauma Research Consortium. [Special Issue]. J Orthop Trauma. 31(4). iii METRC. 2021. Effect of Intrawound Vancomycin Powder in Operatively Treated High- risk Tibia Fractures: A Randomized Clinical Trial. JAMA Surgery. 156(5):e207259- e207259. iv Schmidt AH, Bosse MJ, Obremskey WT, et al. 2018. Continuous near-infrared spectroscopy demonstrates limitations in monitoring the development of acute compartment syndrome in patients with leg injuries. J Bone Joint Surg Am. 100(19):1645-1652. v Schmidt AH, Di J, Zipunnikov V, et al. 2020. Perfusion pressure lacks diagnostic specificity for the diagnosis of acute compartment syndrome. J Orthop Trauma. 34(6):287-293. vi METRC. 2021. Outcomes Following Severe Distal Tibial, Ankle, and/or Mid/Hindfoot Trauma: comparison of limb salvage and transtibial amputation (OUTLET). J Bone Joint Surg Am. 103(17):1588-1597. SOURCE American Academy of Orthopaedic Surgeons