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MechanismOpioid receptors agonists |
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Inactive Indication- |
Drug Highest PhasePhase 2 |
First Approval Ctry. / Loc.- |
First Approval Date- |
/ CompletedNot Applicable [Translation] Phase IIa pilot clinical study of a new drug for preventing relapse: thiophenephine hydrochloride tablets
针对阿片类依赖者应用丁丙诺啡(美沙酮)脱毒或诱导桥接引入盐酸噻吩诺啡片进行防复吸治疗,及既定用药方案下,患者对盐酸噻吩诺啡片耐受的观察,为IIa期试验针对该目标受试者人群的给药方案设计提供依据。
[Translation] The use of buprenorphine (methadone) for detoxification or induced bridging of opioid addicts with the introduction of thiophene hydrochloride tablets for relapse prevention treatment, as well as the observation of patients' tolerance to thiophene hydrochloride tablets under the established medication regimen, provide a basis for the design of dosing regimens for this target subject population in the Phase IIa trial.
/ Not yet recruitingPhase 2 盐酸噻吩诺啡片预防阿片类依赖者脱毒后复吸有效性与安全性的多中心、双盲、随机对照II期临床研究
[Translation] A multicenter, double-blind, randomized controlled phase II clinical study on the efficacy and safety of thiophene hydrochloride tablets in preventing relapse in opioid addicts after detoxification
通过评价盐酸噻吩诺啡片在阿片类依赖者脱毒后预防复吸的有效性与安全性,为后续试验给药方案确定提供科学依据.
[Translation] The effectiveness and safety of thiophene hydrochloride tablets in preventing relapse in opioid addicts after detoxification were evaluated to provide a scientific basis for determining the dosing regimen in subsequent trials.
/ Unknown statusPhase 2IIT A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase Ⅱb Clinical Trial of Thienorphine Hydrochloride Tablets for the Efficacy, Safety, and Optimal Dosing of Relapse Prevention After Opioid Dependence Detoxification
Opioid addiction is common worldwide. Thienorphine hydrochloride is a newly partial opioid receptor agonist drugs. It's affinity with opioid receptors was much higher than opioids, which could effectively prevents opioid dependence by stop opioids competition for opioid receptors and causing opioid dependence. The aim of this research was to determine whether thienorphine hydrochloride would reduce opioid use and better preventing relapse among opioid addicts.
100 Clinical Results associated with Beijing Zidu Hongye Technology Development Co Ltd
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100 Translational Medicine associated with Beijing Zidu Hongye Technology Development Co Ltd