Somatic multicomorbidity and disability in patients with psychiatric disorders in comparison to the general population: a quasi-epidemiological investigation in 54,826 subjects from 40 countries (COMET-G study)

Article

Author: Sánchez de Carmona, Manuel ; Abraham, Seri ; Dodd, Seetal ; Pinto Da Costa, Mariana ; Liewig, Justine ; Khaustova, Olena ; Panteleeva, Liliya ; Saw, Jo Anne ; Stefano, Ramona Di ; Mustač, Filip ; Vrublevska, Jelena ; Bjedov, Sarah ; Koupidis, Sotirios A ; Papava, Ion ; Franza, Francesco ; Nassieb, Amira ; Cabrera Abud, Indira Indiana ; Shirasaka, Tomohiro ; Prezerakos, Panagiotis E ; Ullah, Irfan ; De Berardis, Domenico ; Kopishinskaia, Svetlana ; Shah, Bhumika ; Adorjan, Kristina ; Kazakova, Olga ; Erdelyi-Hamza, Berta ; Zamora Delgado, Sergio ; Morozov, Petr ; Szczegielniak, Anna ; Popkov, Mikhail ; Marčinko, Darko ; Frias, Pedro ; Patsali, Mikaella E ; Mohammed, Muftau ; Pandova, Milena ; Iftene, Felicia ; Ignatenko, Yulia ; Bredicean, Cristina Ana ; Matiekus, Eimantas ; Bobes, Julio ; Raduan, Nor Jannah Nasution ; Mejia, Gabriela ; Berk, Michael ; Khalifa, Doaa ; Stoyanova, Maria ; Malik, Najma Iqbal ; Garay, Cristian J ; Kafali, Helin Yilmaz ; Tohen, Mauricio ; Karakatsoulis, Grigorios N ; Morera González, Daniela ; Alarcón, Renato D ; Corral, Ricardo ; Meza Martínez, Xarah Elenne ; Kulig, Barbara ; Saucedo Martínez, David ; Saiz, Pilar ; Lucena, David De ; Majid, Abdul ; Yashikhina, Anna ; Ninoska Reyes Flores, Elena ; Erzin, Gamze ; Jakšić, Nenad ; Elissa, Anna ; Arai, Kiyomi ; Hilbig, Jan ; Martinez, Stephanie ; Tavormina, Giuseppe ; Gondek, Tomasz M ; Tamasan, Simona Claudia ; Lalljee, Alisha ; Schneidereit, Patricia ; Theodorakis, Pavlos N ; Vysotska, Olga ; Tavormina, Maurilio Giuseppe Maria ; Ismayilova, Jamila ; Iakimova, Rossitza ; Grandinetti, Paolo ; Ahmed, Helal Uddin ; Auwal, Sani Salihu ; Vukovic, Olivera ; García-Portilla, Maria Paz ; Hasan, Tasdik M ; Kovacs, Illes ; Cetkovich, Marcelo ; Memon, Roha Saeed ; Karia, Sagar ; Hossain, Sahadat ; Jakovljević, Miro ; Javed, Afzal ; Pavlichenko, Alexey ; Grau, Arturo ; Crepin, Piirika ; Bukelskis, Laurynas ; Malik, Khamelia ; Mammadzada, Gulay ; Gould, Hilary ; Groudeva, Violeta ; Malashonkova, Evgeniia ; Sousa, Avinash De ; Cortez-Vergara, Carla ; Mahalingappa, Sridevi Sira ; Burkadze, Akaki ; Razali, Salmi ; Muhammad, Nuru Suleiman ; Kosenko, Korneliia ; Navickas, Alvydas ; Vaidya, Ratnaraj ; Silagadze, Ketevan ; Colon-Rivera, Hector ; Smirnova, Daria ; Rebok, Federico ; Skugarevsky, Oleg ; Tukhvatullina, Dina ; Hagin, Michal ; Fountoulakis, Konstantinos N ; Filatova, Viktoriia ; Naor, Mika S ; Castilla-Puentes, Ruby ; Milev, Roumen ; Ismail, Zaliha ; Fountoulakis, Nikolaos K ; Frankova, Iryna ; Bourgin-Duchesnay, Julie ; Koh, Steve ; Mandalia, Bilvesh ; Etchevers, Martin J ; Vargas Ramírez, Francisca ; Harada, Takayuki ; Vega-Dienstmaier, Johann M ; Rewekant, Anna ; Widiasih, Natalia ; Priyanka Elek, Livia ; Pejuskovic, Bojana ; Molina-López, Alejandro ; Spikina, Anna ; Galako, Tatiana ; Sitanggang, Satti ; Falkai, Peter ; Mickevičiūtė, Dalia ; Azreen Hashim, Nurul ; Farcas, Adriana ; Rancans, Elmars ; Marazziti, Donatella ; Bobes-Bascaran, Teresa ; Irarrazaval, Matias ; Okasha, Tarek ; Ibrahim, Mona ; Garcia-Álvarez, Leticia ; Popovic, Dina ; Jakobs, Asaf ; Panfil, Anca-Livia ; Saygili, Görkem ; Rivera-Encinas, María Teresa ; Fedotov, Ilya ; Tsapakis, Eva Maria ; Gonda, Xenia

AbstractBackgroundThe prevalence of medical illnesses is high among patients with psychiatric disorders. The current study aimed to investigate multi-comorbidity in patients with psychiatric disorders in comparison to the general population. Secondary aims were to investigate factors associated with metabolic syndrome and treatment appropriateness of mental disorders.MethodsThe sample included 54,826 subjects (64.73% females; 34.15% males; 1.11% nonbinary gender) from 40 countries (COMET-G study). The analysis was based on the registration of previous history that could serve as a fair approximation for the lifetime prevalence of various medical conditions.ResultsAbout 24.5% reported a history of somatic and 26.14% of mental disorders. Mental disorders were by far the most prevalent group of medical conditions. Comorbidity of any somatic with any mental disorder was reported by 8.21%. One-third to almost two-thirds of somatic patients were also suffering from a mental disorder depending on the severity and multicomorbidity. Bipolar and psychotic patients and to a lesser extent depressives, manifested an earlier (15–20 years) manifestation of somatic multicomorbidity, severe disability, and probably earlier death. The overwhelming majority of patients with mental disorders were not receiving treatment or were being treated in a way that was not recommended. Antipsychotics and antidepressants were not related to the development of metabolic syndrome.ConclusionsThe finding that one-third to almost two-thirds of somatic patients also suffered from a mental disorder strongly suggests that psychiatry is the field with the most trans-specialty and interdisciplinary value and application points to the importance of teaching psychiatry and mental health in medical schools and also to the need for more technocratically oriented training of psychiatric residents.

01 Sep 2023·Social Psychiatry and Psychiatric Epidemiology

Results of the COVID-19 mental health international for the health professionals (COMET-HP) study: depression, suicidal tendencies and conspiracism

Article

Author: Saw, Jo Anne ; Gondek, Tomasz M ; Rancans, Elmars ; Iftene, Felicia ; Bobes-Bascaran, Teresa ; Tamasan, Simona Claudia ; Bourgin-Duchesnay, Julie ; Marčinko, Darko ; Erdelyi-Hamza, Berta ; Kosenko, Korneliia ; Tohen, Mauricio ; Frankova, Iryna ; Mustač, Filip ; Hasan, Tasdik M ; Cetkovich, Marcelo ; Mickevičiūtė, Dalia ; Ismayilova, Jamila ; Malik, Khamelia ; di Stefano, Ramona ; Jakovljević, Miro ; Nassieb, Amira ; Yashikhina, Anna ; Memon, Roha Saeed ; Lalljee, Alisha ; Skugarevsky, Oleg ; Crepin, Piirika ; Auwal, Sani Salihu ; Harada, Takayuki ; Sánchez de Carmona, Manuel ; Grau, Arturo ; García-Portilla, Paz ; Majid, Abdul ; de Lucena, David ; Spikina, Anna ; de Sousa, Avinash ; Dodd, Seetal ; Molina-López, Alejandro ; Mahalingappa, Sridevi Sira ; Panfil, Anca-Livia ; Vukovic, Olivera ; Yilmaz Kafali, Helin ; Pavlichenko, Alexey ; Iqbal Malik, Najma ; Hossain, Sahadat ; Papava, Ion ; Meza Martínez, Xarah Elenne ; Kopishinskaia, Svetlana ; Khalifa, Doaa ; Frias, Pedro ; Mejia, Gabriela ; Mammadzada, Gulay ; Corral, Ricardo ; Hagin, Michal ; Matiekus, Eimantas ; Koh, Steve ; Silagadze, Ketevan ; Morera González, Daniela ; Popkov, Mikhail ; Alarcón, Renato D ; Schneidereit, Patricia ; Razali, Salmi ; Malashonkova, Evgeniia ; Stoyanova, Maria ; Saygili, Görkem ; Garcia-Álvarez, Leticia ; Javed, Afzal ; Theodorakis, Pavlos N ; Zamora Delgado, Sergio ; Ahmed, Helal Uddin ; Ignatenko, Yulia ; Prezerakos, Panagiotis E ; Okasha, Tarek ; Jakšić, Nenad ; Elissa, Anna ; Khaustova, Olena ; Gould, Hilary ; Marazziti, Donatella ; Shirasaka, Tomohiro ; Karia, Sagar ; Elek, Livia Priyanka ; Panteleeva, Liliya ; Vysotska, Olga ; Pinto da Costa, Mariana ; Pejuskovic, Bojana ; Raduan, Nor Jannah Nasution ; Vaidya, Ratnaraj ; Koupidis, Sotirios A ; Muhammad, Nuru Suleiman ; Mohammed, Muftau ; Navickas, Alvydas ; Patsali, Mikaella E ; Saiz, Pilar A ; Bukelskis, Laurynas ; Morozov, Petr ; Tavormina, Giuseppe ; Martinez, Stephanie ; Arai, Kiyomi ; Vargas Ramírez, Francisca ; N Fountoulakis, Konstantinos ; Etchevers, Martin J ; Berk, Michael ; Mandalia, Bilvesh ; Rivera-Encinas, María Teresa ; Grandinetti, Paolo ; Groudeva, Violeta ; Rewekant, Anna ; Kovacs, Illes ; de Berardis, Domenico ; Gonda, Xenia ; Bredicean, Cristina Ana ; Garay, Cristian J ; Liewig, Justine ; Cortez-Vergara, Carla ; Filatova, Viktoriia ; Vrublevska, Jelena ; Pandova, Milena ; Tukhvatullina, Dina ; Popovic, Dina ; Ullah, Irfan ; Erzin, Gamze ; Bobes, Julio ; Burkadze, Akaki ; Vega-Dienstmaier, Johann M ; Shah, Bhumika ; Naor, Mika S ; Saucedo Martínez, David ; Kulig, Barbara ; Ibrahim, Mona ; Rebok, Federico ; Irarrazaval, Matias ; Milev, Roumen ; Cabrera Abud, Indira Indiana ; Falkai, Peter ; Ismail, Zaliha ; N Karakatsoulis, Grigorios ; Smirnova, Daria ; Hilbig, Jan ; Fedotov, Ilya ; Fountoulakis, Nikolaos K ; Abraham, Seri ; Szczegielniak, Anna ; Jacobs, Asaf ; Kazakova, Olga ; Sitanggang, Satti ; Tavormina, Maurilio Giuseppe Maria ; Tsapakis, Eva-Maria ; Franza, Francesco ; Azreen Hashim, Nurul ; Adorjan, Kristina ; Widiasih, Natalia ; Iakimova, Rossitza ; Galako, Tatiana ; Colon-Rivera, Hector ; Reyes Flores, Elena Ninoska ; Farcas, Adriana ; Levaj, Sarah ; Castilla-Puentes, Ruby

INTRODUCTIONThe current study aimed to investigate the rates of anxiety, clinical depression, and suicidality and their changes in health professionals during the COVID-19 outbreak.MATERIALS AND METHODSThe data came from the larger COMET-G study. The study sample includes 12,792 health professionals from 40 countries (62.40% women aged 39.76 ± 11.70; 36.81% men aged 35.91 ± 11.00 and 0.78% non-binary gender aged 35.15 ± 13.03). Distress and clinical depression were identified with the use of a previously developed cut-off and algorithm, respectively.STATISTICAL ANALYSISDescriptive statistics were calculated. Chi-square tests, multiple forward stepwise linear regression analyses, and Factorial Analysis of Variance (ANOVA) tested relations among variables.RESULTSClinical depression was detected in 13.16% with male doctors and 'non-binary genders' having the lowest rates (7.89 and 5.88% respectively) and 'non-binary gender' nurses and administrative staff had the highest (37.50%); distress was present in 15.19%. A significant percentage reported a deterioration in mental state, family dynamics, and everyday lifestyle. Persons with a history of mental disorders had higher rates of current depression (24.64% vs. 9.62%; p < 0.0001). Suicidal tendencies were at least doubled in terms of RASS scores. Approximately one-third of participants were accepting (at least to a moderate degree) a non-bizarre conspiracy. The highest Relative Risk (RR) to develop clinical depression was associated with a history of Bipolar disorder (RR = 4.23).CONCLUSIONSThe current study reported findings in health care professionals similar in magnitude and quality to those reported earlier in the general population although rates of clinical depression, suicidal tendencies, and adherence to conspiracy theories were much lower. However, the general model of factors interplay seems to be the same and this could be of practical utility since many of these factors are modifiable.

01 Apr 2023·Revista Colombiana de Psiquiatría

Ciento cincuenta años de hebefrenia. Una revisión

Review

Author: Daniel R. Martínez

INTRODUCTIONThe publication of Hecker's article on hebephrenia in 1871 was a fundamental milestone for clinical psychiatry. Despite the initial recognition, many voices were raised against this diagnostic category and its limits were attenuated throughout the 20th century until its disappearance at the beginning of this century (along with the other subtypes of schizophrenia) in the DSM and ICD.DISCUSSIONHowever, given the consistency of the clinical picture, there is the possibility of other criteria emerging that would lead its systematic study to continue or recommence. In this sense, the concepts of deficit schizophrenia, hebephrenia as a replacement for schizophrenia as a whole, and Leonhard's hebephrenias as systematic schizophrenias stand out. This article discusses the main diagnostic conflicts of the category of hebephrenia over time, with emphasis on the problems of recent decades.CONCLUSIONSThe concept of hebephrenia has begun to be revalued in recent years, and the concepts of deficit schizophrenia, of hebephrenia as a major category, and of systematic hebephrenias allow further investigation of this foundational picture of clinical psychiatry.

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