A phase Ib/II clinical trial on the safety and efficacy of sirolimus (albumin-bound) combined with different ADCs in patients with advanced solid tumors
A Phase Ib/II Clinical Trial on the Safety and Efficacy of Sirolimus (Albumin-bound) Combined With Different ADCs in Patients With Advanced Solid Tumors
This study adopts a multi-center, open-label, non-randomized trial design. It plans to enroll patients with Advanced solid tumor. Dose-escalation and PK-expansion studies will be carried out to evaluate the safety, tolerability, and preliminary efficacy of sirolimus (albumin-bound) in combination with Different ADCs (DP303c/SYS6043/SYS6002/SYS6010) in this patient population, and to confirm the recommended phase 2 dose (RP2D).
100 Clinical Results associated with EGFR C797S x EGFR T790M x EGFR-Ex19del x Top I
100 Translational Medicine associated with EGFR C797S x EGFR T790M x EGFR-Ex19del x Top I
0 Patents (Medical) associated with EGFR C797S x EGFR T790M x EGFR-Ex19del x Top I