PHASE 2 Study of Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors (GLOBOTRK)
This clinical trial tests how well entrectinib works to treat patients less than 3 years of age with NTRK 1/2/3 or ROS1 fused, high grade glioma or other central nervous system (CNS) tumors.
/ Not yet recruitingPhase 2IIT A Phase II Clinical Study on Precision Treatment of Rare Tumours in China Guided by Patient-Derived Tumor Organoids (PDO) and Next-Generation Sequencing (NGS)
The objective of this Phase II, open-label, multicenter, non-randomised controlled clinical trial is to guide precision treatment for patients with rare tumours based on Patient-Derived Organoids/Next-Generation Sequencing drug screening.
一项在根据生物标志物状态选择的可切除I-III期非小细胞肺癌患者队列中评价多种治疗有效性和安全性的多中心I-III期研究
[Translation] A multicenter phase I-III study evaluating the efficacy and safety of multiple treatments in a cohort of patients with resectable stage I-III non-small cell lung cancer selected by biomarker status
本研究旨在评价多种治疗在早期可切除NSCLC患者中的有效性和/或安全性。队列B1:评价阿来替尼联合化疗在完全切除的II期、IIIA期和选定的IIIB期(仅T3N2;根据AJCC第8版)、ALK阳性NSCLC患者中的安全性;队列B2:在可切除的II、IIIA和选定IIIB期(仅T3N2;根据AJCC第8版)ALK阳性NSCLC患者中评价阿来替尼联合化疗新辅助治疗的有效性
[Translation] This study aims to evaluate the efficacy and/or safety of multiple therapies in patients with early-stage resectable NSCLC. Cohort B1: To evaluate the safety of alectinib combined with chemotherapy in patients with completely resected stage II, IIIA, and selected stage IIIB (only T3N2; according to AJCC 8th edition), ALK-positive NSCLC; Cohort B2: To evaluate the efficacy of alectinib combined with chemotherapy as a neoadjuvant treatment in patients with resectable stage II, IIIA, and selected stage IIIB (only T3N2; according to AJCC 8th edition), ALK-positive NSCLC.
100 Clinical Results associated with ALK x DNA
100 Translational Medicine associated with ALK x DNA
0 Patents (Medical) associated with ALK x DNA